Evidence map›Paper›PMID 40226570›Full record

ArticleSisli Etfal Hastanesi tip bulteni2025

Which Nutritional Scoring System Best Predicts Transplant Outcomes in Allogeneic Stem Cell Recipients? A Comparison of Nutritional Risk Index, Prognostic Nutritional Index, and Controlling Nutritional Status.

Sidika Gulkan Ozkan, Suna Avci, Ada Urusak, Arif Ataberk Buyukyatikci, Kimiaei Ali, Seyedehtina Safaei, Yuksel Altuntas, Yuksel Asli Ozturkmen, Zeynep Asli Durak, Mehmet Serdar Yildiz and 1 more

Abstract read
In one paragraph

Article in Sisli Etfal Hastanesi tip bulteni, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sidika Gulkan OzkanDivision of Hematology, Department of Internal Medicine, Bahcesehir University Faculty of Medicine, Istanbul, Türkiye.
Suna AvciDepartment of Geriatric Medicine, Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Türkiye.
Ada UrusakUniversity of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.
Arif Ataberk BuyukyatikciUniversity of Health Sciences Türkiye, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Türkiye.
Kimiaei AliDivision of Hematology, Department of Internal Medicine, Bahcesehir University Faculty of Medicine, Istanbul, Türkiye.
Seyedehtina SafaeiDivision of Hematology, Department of Internal Medicine, Bahcesehir University Faculty of Medicine, Istanbul, Türkiye.
Yuksel AltuntasDivision of Endocrinology, Department of Internal Medicine, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.
Yuksel Asli OzturkmenDivision of Hematology, Department of Internal Medicine, Sivas Numune Hospital, Sivas, Türkiye.
Zeynep Asli DurakDivision of Hematology, Department of Internal Medicine, Bahcesehir University Faculty of Medicine, Istanbul, Türkiye.
Mehmet Serdar YildizDepartment of Internal Medicine, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.
Hasan Atilla OzkanDivision of Hematology, Department of Internal Medicine, Bahcesehir University Faculty of Medicine, Istanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Nutritional status significantly impacts outcomes in allogeneic hematopoietic stem cell transplantation (allo-HSCT). Among various indices, the Nutritional Risk Index (NRI), Prognostic Nutritional Index (PNI), and Controlling Nutritional Status (CONUT) scores hold potential as prognostic tools. This study compares their predictive utility for transplant outcomes. Methods: A retrospective analysis was conducted on 41 patients who underwent their first allo-HSCT between October 2022 and July 2024. Nutritional scores were calculated using pre-transplant data, and their associations with mortality and non-relapse mortality (NRM) were assessed. Receiver operating characteristic (ROC) curves and multivariable logistic regression were employed to evaluate predictive accuracy. Results: The high CONUT score demonstrated the highest prognostic accuracy for mortality (AUC: 0.771, p=0.026) and NRM (AUC: 0.806, p=0.047). It was the sole independent predictor of mortality (OR: 2.180, p=0.028). Both the NRI (AUC: 0.737, p=0.040) and PNI (AUC: 0.803, p=0.008) were also associated with mortality but lacked independent predictive value. Higher CONUT scores correlated with increased mortality rates. Conclusion: The CONUT score emerged as the most effective nutritional scoring system for predicting mortality in allo-HSCT patients. Its simplicity and integration of key clinical parameters make it a valuable tool for early risk stratification and targeted interventions. Further studies with larger cohorts are warranted to validate these findings and refine nutritional management strategies.

Indexed as

Allogeneic hematopoietic stem cell transplantationCONUT scoreNRInutritional assessmentPNItransplant outcomes

Identifiers

PMID40226570
PMCPMC11983031

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.