ReviewAntioxidants (Basel, Switzerland)2025
A Narrative Review of the Expression and Role of Nitric Oxide in Endometriosis.
Review in Antioxidants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Unlocking Implantation: The Role of Nitric Oxide, NOInternational journal of molecular sciences · 2025Pooled it
- Polyphenol-Rich Wild Fruits of the Indian Himalayas as a Potential Nutraceutical Candidate for the Management of Endometriosis: A Review.Foods (Basel, Switzerland) · 2026Review
- Nitric Oxide Synthase Expression in Endometrium During Physiological Cycle.Physiological research · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Nitric oxide (NO) is a key signaling molecule involved in cellular communication and plays a critical role in various biological processes. Given its dual role in the pathogenesis of endometriosis, we conducted a systematic literature review to explore its mechanisms further. Numerous studies have investigated the expression and role of NO in various diseases, including those in the field of gynecology. However, the expression and role of NO in endometriosis remain a topic of ongoing debate. Therefore, we conducted a comprehensive literature review using the Cochrane Library, EMBASE, Google Scholar, PubMed, and SCOPUS databases to evaluate the induction and role of NO in the pathogenesis of endometriosis. Of the 27 papers ultimately reviewed, 22 (81.4%) reported that NO contributes to the pathogenesis of endometriosis, 3 (11.1%) suggested that NO acts as a protective mechanism against endometriosis, and 2 studies (7.4%) found no association between NO and the pathogenesis of endometriosis. The expression and levels of NO in endometriosis were associated with pregnancy, infertility, menstruation, and pelvic pain. Research conducted on rats and mice demonstrated that NO, nNOS, eNOS, and iNOS play significant roles in the development of endometriosis. Most studies suggested that increased NO levels are associated with the pathogenesis of endometriosis.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.