Evidence map›Paper›PMID 40227329›Full record

ReviewDie Ophthalmologie2025

[New systemic treatment approaches for malignant eyelid tumors].

Michael Simon, Florian T Steinberg, Constantin E Niederau, Philomena A Wawer Matos Reimer, Alexander C Rokohl, Ludwig M Heindl

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Die Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael SimonZentrum für Augenheilkunde, Universität zu Köln, Medizinische Fakultät und Uniklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland. michael.simon1@uk-koeln.de.ORCID http://orcid.org/0000-0003-0540-4509
Florian T SteinbergZentrum für Augenheilkunde, Universität zu Köln, Medizinische Fakultät und Uniklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Constantin E NiederauZentrum für Augenheilkunde, Universität zu Köln, Medizinische Fakultät und Uniklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Philomena A Wawer Matos ReimerZentrum für Augenheilkunde, Universität zu Köln, Medizinische Fakultät und Uniklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Alexander C RokohlZentrum für Augenheilkunde, Universität zu Köln, Medizinische Fakultät und Uniklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.
Ludwig M HeindlZentrum für Augenheilkunde, Universität zu Köln, Medizinische Fakultät und Uniklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant tumors of the eyelids represent a diagnostic and therapeutic challenge. Modern treatment approaches, such as targeted treatment and immunotherapy are becoming increasingly more important, particularly in advanced and metastatic stages; however, these can cause side effects such as fatigue, skin reactions and gastrointestinal complaints, which require close monitoring. An effective treatment option for advanced, metastasized or inoperable basal cell carcinoma is the well-manageable oral treatment with hedgehog inhibitors; however, these innovative, systemic treatment approaches require an individually adapted management, which is determined by an interdisciplinary tumor board and accompanied by a specialized, multiprofessional team to ensure optimal patient care.

Indexed as

Antineoplastic AgentsBasal Cell CarcinomaEyelid NeoplasmsImmunotherapyMolecular Targeted TherapyHedgehog ProteinsHumansAntineoplastic AgentsHedgehog ProteinsAdvanced diseaseBasal cell carcinomaImmunotherapyMetastasisSquamous cell carcinoma

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.