Evidence map›Paper›PMID 40227544›Full record

ArticleCurrent cardiology reports2025

Cardiovascular Outcomes After Acute Coronary Syndrome in Persons Living with HIV: A Scoping Review.

David Iskhakov, Julie N Deleger, Jorge Plutzky, Virginia A Triant, Emily P Hyle

Abstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in Current cardiology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David IskhakovDepartment of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Julie N DelegerMedical Practice Evaluation Center, Massachusetts General Hospital, Boston, MA, USA.
Jorge PlutzkyCardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Virginia A TriantDepartment of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Emily P HyleDepartment of Medicine, Massachusetts General Hospital, Boston, MA, USA. ehyle@mgh.harvard.edu.

Funding

The Impact of Hearing Loss Treatment Scale-Up in Persons Aging with HIV on Dementia Risk, Quality of Life, and Healthcare CostsR01AG069575 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI HYLE, EMILY PARKER · 2021 to 2025
$4.6M
Enhancing cardiovascular risk estimation in individuals aging with HIV/HCV co-infectionR01AG062393 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI TRIANT, VIRGINIA ATHENA · 2019 to 2023
$4.5M
Enhancing cardiovascular risk prediction in HIV using novel factors in the REPRIEVE trialR01HL169015 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Virginia Athena Triant · 2024 to 2026
$2.2M
NHLBI NIH HHS R01 HL169015NHLBI NIH HHS R01HL169015NIA NIH HHS R01 AG062393NIA NIH HHS R01AG062393NIA NIH HHS R01 AG069575NIA NIH HHS R01AG069575
6 · The paper itself

Abstract

purpose of reviewOver the past twenty-five years, a growing body of research has investigated outcomes after an acute coronary syndrome (ACS) event in persons with HIV (PWH). In this scoping review, we assessed the published literature on outcomes after a prior ACS event in PWH compared to persons without HIV (PWoH) in the US and Europe. RECENT

findingsOf 27 studies of secondary prevention of cardiovascular disease, 15 studies found a greater incidence of recurrent ACS, heart failure, in-stent thrombosis, revascularization, restenosis, and mortality in PWH after a prior ACS event compared to PWoH. PWH were more likely to present with STEMI, less likely to receive percutaneous coronary intervention, and more likely to exhibit an active inflammatory state. The remaining 12 studies found no significant difference in outcomes after a prior ACS event. PWH may face an increased risk of adverse outcomes after ACS that differ in presentation and management compared with PWoH. Larger observational studies are needed to assess outcomes after a prior ACS event in PWH compared to PWoH and improve clinical management.

Indexed as

Acute Coronary SyndromeHIV InfectionsHumansPercutaneous Coronary InterventionSecondary PreventionAcute coronary syndromeCardiovascular OutcomesHuman immunodeficiency virusPersons living with HIV

Identifiers

PMID40227544
PMCPMC11999250

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.