Evidence map›Paper›PMID 40230596›Full record

ArticleMolecular imaging

Preliminary Exploration of Al

Shibo Guo, Zhehao Lyu, Chunyu Duan, Hui Wang, Peng Xu, Wei Han, Peng Fu

Abstract read
In one paragraph

Article in Molecular imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Parametric mapping of dynamicCancer imaging : the official publication of the International Cancer Imaging Society · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shibo GuoDepartment of Nuclear Medicine, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China.ORCID 0000-0003-3314-4089
Zhehao LyuDepartment of Nuclear Medicine, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China.
Chunyu DuanDepartment of Nuclear Medicine, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China.
Hui WangDepartment of Rheumatology and Immunology, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China.
Peng XuDepartment of Nuclear Medicine, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China.
Wei HanDepartment of Nuclear Medicine, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China.
Peng FuDepartment of Nuclear Medicine, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China.ORCID 0000-0002-9860-9150

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ankylosing spondylitis (AS) is characterized by inflammation and osteoblastic changes in the sacroiliac joint. As a potential imaging method for the early assessment of AS, positron emission tomography (PET) can quantify systemic disease activity, which is conducive to monitoring the progression of disease activity and assisting in evaluating the efficacy of the treatment. Objective: The study was to evaluate the diagnostic value of aluminium-[ Material and Methods: Twenty AS participants who met the Assessment of SpondyloArthritis international Society criteria and were in an active disease stage were included in this study from May 2022 to April 2023. Sixteen healthy controls were also inrolled. All participants underwent Al Results: A total of 2820 joints were observed in 20 participants (median age 34.5,[21-61]range, 15 men), with a PJC of 1300 (46.7%), and 39 positive uptakes were found in 40 sacroiliac joints (97.5%). PET/CT images revealed FAPI-04 uptake in both sacroiliac joints in 2 participants without radiographic sacroiliitis in the early stages of AS and varying degrees of uptake in the sacroiliac joints and spinal joints in the remaining participants. PJC and SUVR were positively correlated with most clinical assessments and laboratory findings ( Conclusion: Al

Indexed as

Fluorine RadioisotopesPositron Emission Tomography Computed TomographySpondylitis, AnkylosingAdultFemaleHumansMaleMiddle AgedProspective StudiesYoung AdultFluorine Radioisotopesankylosing spondylitisfibroblast activation proteininflammationPET/CT

Identifiers

PMID40230596
PMCPMC11995437

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.