Evidence map›Paper›PMID 40230695›Full record

ArticleFrontiers in pharmacology2025

The mechanism study of quercetin isolated from

Yan Chen, Fajian Ren, Nannan Yang, Qiwen Xiang, Song Gao, Wei Pu, Zhou Yang, Qiuyan Liu, Shajie Luo, Chaolong Rao

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Iturin derived fromiScience · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yan Chen *School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Fajian Ren *School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Nannan YangSchool of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Qiwen XiangSchool of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Song GaoSchool of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Wei PuSchool of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Zhou YangSchool of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Qiuyan LiuSchool of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Shajie LuoCollege of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Chaolong RaoSchool of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: As a resource with a variety of medicinal and edible values, Aim of the study: The aim of this study was to predict the main active metabolites in Materials and Methods: MAFLD mouse model and cell model were established to evaluate the effect of active components in Results: Quercetin can regulate the liver lipid metabolites of MAFLD mice through the Glycerophospholipid metabolic pathway, thereby improving liver lipid accumulation and liver injury. At the same time, quercetin can also improve MAFLD by reducing oleic acid-induced lipid accumulation in HepG2 cells, and inhibit ferroptosis through the p38 MAPK/ERK signaling pathway, thereby alleviating the progression of MAFLD. Conclusion: Quercetin isolated from

Indexed as

lipidomicsmetabolic-associated fatty liver diseasequercetintranscriptomicsZanthoxylum bungeanum maxim.

Identifiers

PMID40230695
PMCPMC11994740

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.