Evidence map›Paper›PMID 40230697›Full record

SynthesisFrontiers in pharmacology2025

Efficacy and safety of Tanshinone capsule in Acne vulgaris: a systematic review and meta-analysis.

Yutong Deng, Ruli Feng, Bo Hu, Xuewen Ren, Fengchuan Zhang, Huishang Feng, Xuewan Wang, Yatong Li, Tangyunni Liu, Lingling Cai and 1 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yutong Deng *Beijing University of Chinese Medicine, Beijing, China.
Ruli Feng *Beijing University of Chinese Medicine, Beijing, China.
Bo HuDepartment of Dermatology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Xuewen RenDepartment of Dermatology, Shanxi Traditional Chinese Medical Hospital, Shanxi, China.
Fengchuan ZhangDepartment of Dermatology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Huishang FengDepartment of Dermatology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Xuewan WangBeijing University of Chinese Medicine, Beijing, China.
Yatong LiBeijing University of Chinese Medicine, Beijing, China.
Tangyunni LiuBeijing University of Chinese Medicine, Beijing, China.
Lingling CaiDepartment of Dermatology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Yuanwen LiDepartment of Dermatology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To evaluate the efficacy and safety of Tanshinone capsule as a complementary therapy in managing of Acne Vulgaris. Methods: A systematic search of six databases was conducted to identify relevant randomized controlled trials (RCTs) from each database for nearly 20 years (from 1 Jan 2004, to 1 June 2024). The Cochrane Handbook was used to evaluate the risk of bias. Meta-analysis was performed using Review Manager 5.4.1, and publication bias was assessed the Stata SE 12.0 software. GRADEpro was used to assess the quality of the evidence. Results: A total of 2,969 participants from 28 studies were included. We found that Tanshinone capsules can reduce acne recurrence rates [risk ratio ( Conclusion: Tanshinone capsules can relieve the symptoms of acne vulgaris, regulate inflammatory cytokines and hormone levels in patients, and reduce recurrence. However, due to the limitations of this study, more multi-center and large-sample studies are needed to confirm these conclusions. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024562320, identifier CRD42024562320.

Indexed as

Acne vulgarismeta-analysisrandomized controlled trialsystematic reviewTanshinone capsule

Identifiers

PMID40230697
PMCPMC11994734

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.