ArticleARYA atherosclerosis2022
The relationship between lipid profile after fat loading and coronary artery disease severity assessed by SYNTAX score.
Article in ARYA atherosclerosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03175393 (Relation Between Postprandial Lipogram and Coronary Artery Disease Severity), which is not on this map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Relation Between Postprandial Lipogram and Coronary Artery Disease Severity
Who cites it
2 citing papers in PubMed.
- Roles of Single Nucleotide Polymorphisms ofReviews in cardiovascular medicine · 2024Article
- Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundDyslipidemia is an established risk factor for coronary artery disease (CAD). Despite this, only half of CAD patients present with fasting dyslipidemia. Some reports have linked postprandial lipemia to atherosclerosis. We aimed to test the relationship between postprandial lipid profile (after fat loading) and CAD severity assessed by the SYNTAX score.
methodWe included 53 patients with documented CADs. We checked both fasting and postprandial (2 hours) lipograms after fat loading with 17 g/body surface area (m2). Then we assessed CAD severity via coronary angiography using the SYNTAX score. Our study is registered in clinicaltrials.gov (NCT03175393).
results53 patients with age 57.9 ± 7.82 were recuirted. 36 (68% ) of them were male .We observed a significant increase in postprandial triglycerides (TGs) (154.3 ±73.2 vs. 128.1 ± 69.4 mg/dl; P < 0.001), very-low-density lipoproteins (VLDL) (30.8 ± 14.6 vs. 25.6 ± 13.9 mg/dl; P < 0.001) as well as a significant decrease in the postprandial level of total cholesterol (162.4 ± 45.9 vs. 168.3 ± 46.0 mg/dl; P = 0.03) in comparison to their fasting level. We found that the SYNTAX score had a significant positive moderate correlation with 2-hour postprandial TGs (r = 0.55; P < 0.001) and 2-hour postprandial VLDL (r = 0.50; P < 0.001).Based on the current study, predictors of high Syntax score were older age OR: 1.23(1.11-3.47; P< 0.001) post-prandial triglyceride 2.34 (1.89-5.66; P< 0.001) and post-prandial VLDL 1.76 (1.50-3.49; P< 0.001).
conclusionPostprandial lipograms, especially TGs, are significantly and positively related to CAD severity.
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