ReviewRadiology2025
Requirements for AI Development and Reporting for MRI Prostate Cancer Detection in Biopsy-Naive Men: PI-RADS Steering Committee, Version 1.0.
Abstract readReview
In one paragraph
Review in Radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Reference standards in AI-assisted MRI readings in prostate cancer screening: primetime for benchmarking.European radiology · 2026Article
- Artificial Intelligence Reporting Guidelines in Radiology: A Systematic Review.Diagnostics (Basel, Switzerland) · 2026Review
- Artificial intelligence and radiologists in prostate MRI: Competitors or collaborators?European radiology · 2026Article
- Artificial intelligence in prostate MRI: Comparative diagnostic performance in a high-prevalence cohort.Acta radiologica (Stockholm, Sweden : 1987) · 2026Article
- Shifting from black box decisions to informed decision-making in using artificial intelligence to analyze prostate MRI.Abdominal radiology (New York) · 2026Review
- Navigating PI-RADS v2.1 in clinical practice: pitfalls, variability, and the supportive role of AI.Abdominal radiology (New York) · 2026Review
- The evolving PI-RADS paradigm.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Review
- Integrating Multiparametric MRI and PSMA PET Imaging in Prostate Cancer: Toward a Unified Diagnostic and Risk-Stratification Paradigm.Medicina (Kaunas, Lithuania) · 2026Review
- Radio-pathomic maps of histo-morphometric features trained with whole mount prostate histology distinguish prostate cancer on MP-MRI.medRxiv : the preprint server for health sciences · 2026Article
- Zero-Shot PI-RADS Version 2.1 Scoring with ChatGPT-4 Turbo and Llama 3: Diagnostic Performance and Agreement with Abdominal Radiologists.Radiology. Imaging cancer · 2026Article
- Artificial intelligence in prostate cancer: navigating the new frontier of precision uro-oncology.American journal of clinical and experimental urology · 2025Review
Corrections and comments
- Commented on by
Authors and funding
15 authors.
Baris TurkbeyFrom the Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 (B.T.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (H.H.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.F., C.M.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Md (K.J.M.); Department of Radiology, Weill Cornell Medicine/New York Presbyterian, New York, NY (D.J.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Rome, Italy (V.P.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands (I.G.S.); Department of Surgery, Division of Urology, University of Maryland School of Medicine, Baltimore, Md (M.M.S.); Division of Surgery Interventional Science, University College London, London, UK (C.M.M.); Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK (C.M.M.); Department of Urinary and Vascular Imaging, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France (O.R.); Faculté de Médecine Lyon Est, Université de Lyon, Université Lyon 1, Lyon, France (O.R.); Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio (L.K.B.); Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK (A.R.P.); Joint Department of Medical Imaging, Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada (M.A.H.); and Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (M.A.H.).ORCID 0000-0003-0853-6494
Henkjan HuismanFrom the Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 (B.T.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (H.H.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.F., C.M.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Md (K.J.M.); Department of Radiology, Weill Cornell Medicine/New York Presbyterian, New York, NY (D.J.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Rome, Italy (V.P.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands (I.G.S.); Department of Surgery, Division of Urology, University of Maryland School of Medicine, Baltimore, Md (M.M.S.); Division of Surgery Interventional Science, University College London, London, UK (C.M.M.); Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK (C.M.M.); Department of Urinary and Vascular Imaging, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France (O.R.); Faculté de Médecine Lyon Est, Université de Lyon, Université Lyon 1, Lyon, France (O.R.); Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio (L.K.B.); Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK (A.R.P.); Joint Department of Medical Imaging, Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada (M.A.H.); and Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (M.A.H.).ORCID 0000-0001-6753-3221
Andriy FedorovFrom the Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 (B.T.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (H.H.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.F., C.M.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Md (K.J.M.); Department of Radiology, Weill Cornell Medicine/New York Presbyterian, New York, NY (D.J.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Rome, Italy (V.P.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands (I.G.S.); Department of Surgery, Division of Urology, University of Maryland School of Medicine, Baltimore, Md (M.M.S.); Division of Surgery Interventional Science, University College London, London, UK (C.M.M.); Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK (C.M.M.); Department of Urinary and Vascular Imaging, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France (O.R.); Faculté de Médecine Lyon Est, Université de Lyon, Université Lyon 1, Lyon, France (O.R.); Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio (L.K.B.); Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK (A.R.P.); Joint Department of Medical Imaging, Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada (M.A.H.); and Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (M.A.H.).
Katarzyna J MacuraFrom the Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 (B.T.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (H.H.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.F., C.M.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Md (K.J.M.); Department of Radiology, Weill Cornell Medicine/New York Presbyterian, New York, NY (D.J.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Rome, Italy (V.P.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands (I.G.S.); Department of Surgery, Division of Urology, University of Maryland School of Medicine, Baltimore, Md (M.M.S.); Division of Surgery Interventional Science, University College London, London, UK (C.M.M.); Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK (C.M.M.); Department of Urinary and Vascular Imaging, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France (O.R.); Faculté de Médecine Lyon Est, Université de Lyon, Université Lyon 1, Lyon, France (O.R.); Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio (L.K.B.); Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK (A.R.P.); Joint Department of Medical Imaging, Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada (M.A.H.); and Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (M.A.H.).ORCID 0000-0002-8469-2125
Daniel J MargolisFrom the Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 (B.T.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (H.H.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.F., C.M.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Md (K.J.M.); Department of Radiology, Weill Cornell Medicine/New York Presbyterian, New York, NY (D.J.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Rome, Italy (V.P.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands (I.G.S.); Department of Surgery, Division of Urology, University of Maryland School of Medicine, Baltimore, Md (M.M.S.); Division of Surgery Interventional Science, University College London, London, UK (C.M.M.); Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK (C.M.M.); Department of Urinary and Vascular Imaging, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France (O.R.); Faculté de Médecine Lyon Est, Université de Lyon, Université Lyon 1, Lyon, France (O.R.); Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio (L.K.B.); Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK (A.R.P.); Joint Department of Medical Imaging, Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada (M.A.H.); and Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (M.A.H.).ORCID 0000-0001-8212-707X
Valeria PanebiancoFrom the Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 (B.T.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (H.H.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.F., C.M.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Md (K.J.M.); Department of Radiology, Weill Cornell Medicine/New York Presbyterian, New York, NY (D.J.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Rome, Italy (V.P.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands (I.G.S.); Department of Surgery, Division of Urology, University of Maryland School of Medicine, Baltimore, Md (M.M.S.); Division of Surgery Interventional Science, University College London, London, UK (C.M.M.); Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK (C.M.M.); Department of Urinary and Vascular Imaging, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France (O.R.); Faculté de Médecine Lyon Est, Université de Lyon, Université Lyon 1, Lyon, France (O.R.); Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio (L.K.B.); Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK (A.R.P.); Joint Department of Medical Imaging, Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada (M.A.H.); and Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (M.A.H.).ORCID 0000-0001-8466-918X
Aytekin OtoFrom the Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 (B.T.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (H.H.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.F., C.M.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Md (K.J.M.); Department of Radiology, Weill Cornell Medicine/New York Presbyterian, New York, NY (D.J.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Rome, Italy (V.P.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands (I.G.S.); Department of Surgery, Division of Urology, University of Maryland School of Medicine, Baltimore, Md (M.M.S.); Division of Surgery Interventional Science, University College London, London, UK (C.M.M.); Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK (C.M.M.); Department of Urinary and Vascular Imaging, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France (O.R.); Faculté de Médecine Lyon Est, Université de Lyon, Université Lyon 1, Lyon, France (O.R.); Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio (L.K.B.); Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK (A.R.P.); Joint Department of Medical Imaging, Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada (M.A.H.); and Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (M.A.H.).ORCID 0000-0003-4325-2489
Ivo G SchootsFrom the Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 (B.T.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (H.H.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.F., C.M.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Md (K.J.M.); Department of Radiology, Weill Cornell Medicine/New York Presbyterian, New York, NY (D.J.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Rome, Italy (V.P.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands (I.G.S.); Department of Surgery, Division of Urology, University of Maryland School of Medicine, Baltimore, Md (M.M.S.); Division of Surgery Interventional Science, University College London, London, UK (C.M.M.); Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK (C.M.M.); Department of Urinary and Vascular Imaging, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France (O.R.); Faculté de Médecine Lyon Est, Université de Lyon, Université Lyon 1, Lyon, France (O.R.); Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio (L.K.B.); Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK (A.R.P.); Joint Department of Medical Imaging, Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada (M.A.H.); and Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (M.A.H.).ORCID 0000-0002-9804-0603
M Minhaj SiddiquiFrom the Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 (B.T.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (H.H.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.F., C.M.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Md (K.J.M.); Department of Radiology, Weill Cornell Medicine/New York Presbyterian, New York, NY (D.J.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Rome, Italy (V.P.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands (I.G.S.); Department of Surgery, Division of Urology, University of Maryland School of Medicine, Baltimore, Md (M.M.S.); Division of Surgery Interventional Science, University College London, London, UK (C.M.M.); Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK (C.M.M.); Department of Urinary and Vascular Imaging, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France (O.R.); Faculté de Médecine Lyon Est, Université de Lyon, Université Lyon 1, Lyon, France (O.R.); Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio (L.K.B.); Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK (A.R.P.); Joint Department of Medical Imaging, Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada (M.A.H.); and Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (M.A.H.).ORCID 0000-0002-4484-6820
Caroline M MooreFrom the Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 (B.T.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (H.H.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.F., C.M.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Md (K.J.M.); Department of Radiology, Weill Cornell Medicine/New York Presbyterian, New York, NY (D.J.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Rome, Italy (V.P.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands (I.G.S.); Department of Surgery, Division of Urology, University of Maryland School of Medicine, Baltimore, Md (M.M.S.); Division of Surgery Interventional Science, University College London, London, UK (C.M.M.); Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK (C.M.M.); Department of Urinary and Vascular Imaging, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France (O.R.); Faculté de Médecine Lyon Est, Université de Lyon, Université Lyon 1, Lyon, France (O.R.); Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio (L.K.B.); Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK (A.R.P.); Joint Department of Medical Imaging, Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada (M.A.H.); and Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (M.A.H.).ORCID 0000-0003-0202-7912
Olivier RouvièreFrom the Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 (B.T.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (H.H.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.F., C.M.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Md (K.J.M.); Department of Radiology, Weill Cornell Medicine/New York Presbyterian, New York, NY (D.J.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Rome, Italy (V.P.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands (I.G.S.); Department of Surgery, Division of Urology, University of Maryland School of Medicine, Baltimore, Md (M.M.S.); Division of Surgery Interventional Science, University College London, London, UK (C.M.M.); Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK (C.M.M.); Department of Urinary and Vascular Imaging, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France (O.R.); Faculté de Médecine Lyon Est, Université de Lyon, Université Lyon 1, Lyon, France (O.R.); Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio (L.K.B.); Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK (A.R.P.); Joint Department of Medical Imaging, Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada (M.A.H.); and Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (M.A.H.).ORCID 0000-0002-0030-478X
Leonardo K BittencourtFrom the Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 (B.T.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (H.H.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.F., C.M.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Md (K.J.M.); Department of Radiology, Weill Cornell Medicine/New York Presbyterian, New York, NY (D.J.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Rome, Italy (V.P.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands (I.G.S.); Department of Surgery, Division of Urology, University of Maryland School of Medicine, Baltimore, Md (M.M.S.); Division of Surgery Interventional Science, University College London, London, UK (C.M.M.); Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK (C.M.M.); Department of Urinary and Vascular Imaging, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France (O.R.); Faculté de Médecine Lyon Est, Université de Lyon, Université Lyon 1, Lyon, France (O.R.); Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio (L.K.B.); Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK (A.R.P.); Joint Department of Medical Imaging, Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada (M.A.H.); and Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (M.A.H.).ORCID 0000-0001-9175-9626
Anwar R PadhaniFrom the Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 (B.T.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (H.H.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.F., C.M.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Md (K.J.M.); Department of Radiology, Weill Cornell Medicine/New York Presbyterian, New York, NY (D.J.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Rome, Italy (V.P.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands (I.G.S.); Department of Surgery, Division of Urology, University of Maryland School of Medicine, Baltimore, Md (M.M.S.); Division of Surgery Interventional Science, University College London, London, UK (C.M.M.); Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK (C.M.M.); Department of Urinary and Vascular Imaging, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France (O.R.); Faculté de Médecine Lyon Est, Université de Lyon, Université Lyon 1, Lyon, France (O.R.); Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio (L.K.B.); Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK (A.R.P.); Joint Department of Medical Imaging, Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada (M.A.H.); and Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (M.A.H.).ORCID 0000-0002-5830-5777
Clare M TempanyFrom the Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 (B.T.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (H.H.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.F., C.M.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Md (K.J.M.); Department of Radiology, Weill Cornell Medicine/New York Presbyterian, New York, NY (D.J.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Rome, Italy (V.P.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands (I.G.S.); Department of Surgery, Division of Urology, University of Maryland School of Medicine, Baltimore, Md (M.M.S.); Division of Surgery Interventional Science, University College London, London, UK (C.M.M.); Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK (C.M.M.); Department of Urinary and Vascular Imaging, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France (O.R.); Faculté de Médecine Lyon Est, Université de Lyon, Université Lyon 1, Lyon, France (O.R.); Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio (L.K.B.); Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK (A.R.P.); Joint Department of Medical Imaging, Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada (M.A.H.); and Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (M.A.H.).ORCID 0000-0002-1642-9720
Masoom A HaiderFrom the Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 (B.T.); Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (H.H.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.F., C.M.T.); The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Md (K.J.M.); Department of Radiology, Weill Cornell Medicine/New York Presbyterian, New York, NY (D.J.M.); Department of Radiological Sciences, Oncology and Pathology, Sapienza University, Rome, Italy (V.P.); Department of Radiology, University of Chicago, Chicago, Ill (A.O.); Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands (I.G.S.); Department of Surgery, Division of Urology, University of Maryland School of Medicine, Baltimore, Md (M.M.S.); Division of Surgery Interventional Science, University College London, London, UK (C.M.M.); Department of Urology, University College London Hospitals NHS Foundation Trust, London, UK (C.M.M.); Department of Urinary and Vascular Imaging, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France (O.R.); Faculté de Médecine Lyon Est, Université de Lyon, Université Lyon 1, Lyon, France (O.R.); Department of Radiology, University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, Cleveland, Ohio (L.K.B.); Paul Strickland Scanner Centre, Mount Vernon Hospital, Middlesex, UK (A.R.P.); Joint Department of Medical Imaging, Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada (M.A.H.); and Lunenfeld-Tanenbaum Research Institute, Toronto, Canada (M.A.H.).ORCID 0000-0002-7165-8315
Funding
TRD 3 - Enabling Technologies for Intraprocedural GuidanceP41EB028741 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI Nobuhiko Hata, CLARE M TEMPANY · 2021 to 2026
$10.7MDevelopment of fast diffusion magnetic resonance fingerprinting of the prostate to avoid unnecessary biopsiesR01CA292091 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI Yong Chen, Leonardo Kayat Bittencourt · 2024 to 2026
$3.2MNCI NIH HHS R01 CA292091NIBIB NIH HHS P41 EB028741
Abstract
This document defines the key considerations for developing and reporting an artificial intelligence (AI) interpretation model for the detection of clinically significant prostate cancer (PCa) at MRI in biopsy-naive men with a positive clinical screening status. Specific data and performance metric requirements and a checklist are provided for this use case. Data requirements emphasize the need for sufficient information to provide transparency and characterization of training and test data. The definition of a true-negative examination (which includes a minimum of 2-year follow-up), the need for image quality assessments, and nonimaging metadata requirements are provided. Performance metrics ranges are included, such as a cancer detection rate of 40%-70% for Prostate Imaging Reporting and Data System, or PI-RADS, 4 or higher lesions and demonstration of equivalent or better than human performance using receiver operating characteristic and precision-recall curves. The use of open datasets such as those used in the AI challenge model is encouraged. The study design should include conformity with the Checklist for Artificial Intelligence in Medical Imaging requirements. This article should be taken in the context of the current and evolving regulatory landscape. This review provides guidance based on subspeciality expertise in prostate MRI and will hopefully accelerate the clinical translation of AI in PCa detection.
Indexed as
Artificial IntelligenceImage Interpretation, Computer-AssistedMagnetic Resonance ImagingProstatic NeoplasmsHumansMaleProstate
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.