Evidence mapPaperPMID 40232500Full record

ArticleWiener klinische Wochenschrift2025

Markers for the angiogenic potential of fat grafts.

Maryana Teufelsbauer, Sandra Stickler, Marie-Therese Eggerstorfer, Dennis C Hammond, Clemens Lang, Gerhard Hamilton

Abstract read
In one paragraph

Article in Wiener klinische Wochenschrift, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Plant Exosome Injection: A New Boost for Postlaser Vascular Repair.The Journal of clinical and aesthetic dermatology · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maryana TeufelsbauerDepartment of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Vienna, 1090, Vienna, Austria.
Sandra SticklerInstitute of Pharmacology, Medical University of Vienna, Waehringerstraße 13A, 1090, Vienna, Austria.
Marie-Therese EggerstorferInstitute of Pharmacology, Medical University of Vienna, Waehringerstraße 13A, 1090, Vienna, Austria.
Dennis C HammondCenter for Breast and Body Contouring, 49546, Grand Rapids, MI, USA.
Clemens LangDepartment of Trauma Surgery, Hospital Donaustadt, 1220, Vienna, Austria.
Gerhard HamiltonInstitute of Pharmacology, Medical University of Vienna, Waehringerstraße 13A, 1090, Vienna, Austria. gerhard.hamilton@meduniwien.ac.at.ORCID http://orcid.org/0000-0002-4038-5182

Funding

Medical Scientific Fund of the Mayor of the City of Vienna 22214
6 · The paper itself

Abstract

backgroundFat grafting is widely utilized in reconstructive and esthetic plastic surgery, typically with minimal complications. Nevertheless, the occurrence of fat necrosis is dependent on the technique used for fat extraction, tissue processing and the volume of the graft. The longevity of the graft critically depends on the presence of adipose-derived stromal cells (ADSC) and their promotion of a reconstituted vascular supply.

objectiveThis study seeks to determine whether there are differences in 13 angiogenesis-related adipokines based on their grouping by vascular endothelial growth factor (VEGF) expression levels.

methodsThe expression of 14 adipokines related to angiogenesis in 12 cultured ADSCs was evaluated using Human Adipokine Profiler kits, which simultaneously detect 58 mediators. Adipokines of the high and low VEGF expression groups were evaluated for their expression of the remaining 13 angiogenic proteins.

resultsWe were able to show that there are significant differences in VEGF

conclusionThe VEGF has been described as a key angiogenic factor in fat grafts that may be linked to successful grafting; however, two of the fat samples analyzed exhibited high expression of VEGF but lacked significant co-expression of a range of other angiogenic factors. Thus, the assessment of the expression of predisposing mediators for graft angiogenesis for wound healing or contouring should include further angiogenesis promoters aside VEGF as parameters.

Indexed as

AdipokinesAdipose TissueNeovascularization, PhysiologicVascular Endothelial Growth Factor ABiomarkersCells, CulturedFemaleHumansMaleMiddle AgedAdipokinesBiomarkersVascular Endothelial Growth Factor AAdipokinesAdipose-derived stromal cellsAngiogenesisLiposuctionVEGF

Identifiers

PMID40232500
PMCPMC12592318

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.