Evidence mapPaperPMID 40233166Full record

ArticleCirculation. Cardiovascular interventions2025

Repeatability and Correlation of Coronary Physiology Indices Measured With Bolus and Continuous Thermodilution.

Christopher C Y Wong, Luke P Dawson, Pascal Theriault-Lauzier, Annette Skoda, Helen Luikart, Jennifer A Tremmel, Kiran K Khush, William F Fearon

Abstract readComparative Study
In one paragraph

Article in Circulation. Cardiovascular interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christopher C Y WongDivision of Cardiovascular Medicine, Stanford University School of Medicine and Stanford Cardiovascular Institute, CA (C.C.Y.W., L.P.D., P.T.-L., A.S., H.L., J.A.T., K.K.K., W.F.F.).ORCID 0000-0002-0180-0072
Luke P DawsonDivision of Cardiovascular Medicine, Stanford University School of Medicine and Stanford Cardiovascular Institute, CA (C.C.Y.W., L.P.D., P.T.-L., A.S., H.L., J.A.T., K.K.K., W.F.F.).ORCID 0000-0003-3789-5808
Pascal Theriault-LauzierDivision of Cardiovascular Medicine, Stanford University School of Medicine and Stanford Cardiovascular Institute, CA (C.C.Y.W., L.P.D., P.T.-L., A.S., H.L., J.A.T., K.K.K., W.F.F.).ORCID 0000-0002-6931-2673
Annette SkodaDivision of Cardiovascular Medicine, Stanford University School of Medicine and Stanford Cardiovascular Institute, CA (C.C.Y.W., L.P.D., P.T.-L., A.S., H.L., J.A.T., K.K.K., W.F.F.).
Helen LuikartDivision of Cardiovascular Medicine, Stanford University School of Medicine and Stanford Cardiovascular Institute, CA (C.C.Y.W., L.P.D., P.T.-L., A.S., H.L., J.A.T., K.K.K., W.F.F.).ORCID 0000-0002-9782-4449
Jennifer A TremmelDivision of Cardiovascular Medicine, Stanford University School of Medicine and Stanford Cardiovascular Institute, CA (C.C.Y.W., L.P.D., P.T.-L., A.S., H.L., J.A.T., K.K.K., W.F.F.).ORCID 0000-0001-6620-9139
Kiran K KhushDivision of Cardiovascular Medicine, Stanford University School of Medicine and Stanford Cardiovascular Institute, CA (C.C.Y.W., L.P.D., P.T.-L., A.S., H.L., J.A.T., K.K.K., W.F.F.).ORCID 0000-0001-9697-5926
William F FearonDivision of Cardiovascular Medicine, Stanford University School of Medicine and Stanford Cardiovascular Institute, CA (C.C.Y.W., L.P.D., P.T.-L., A.S., H.L., J.A.T., K.K.K., W.F.F.).ORCID 0000-0003-1799-1368

Funding

NHLBI NIH HHS R33 HL139929NHLBI NIH HHS R61 HL139929
6 · The paper itself

Abstract

backgroundPrevious studies have shown weak agreement between coronary physiology indices derived from continuous and bolus thermodilution, and suggested greater variability with bolus thermodilution measurements. This study aimed to evaluate the repeatability and correlation of continuous and bolus thermodilution-derived physiology indices in cardiac transplant recipients.

methodsPaired fractional flow reserve (FFR), coronary flow reserve (CFR), index of microcirculatory resistance (IMR), absolute hyperemic resistance (R

resultsIn 20 patients, IMR was more repeatable than CFR and MRR derived from either continuous thermodilution (intraclass correlation coefficient, 0.95 versus 0.70 and 0.59;

conclusionsIn cardiac transplant recipients, IMR had superior repeatability compared with CFR and MRR derived from either bolus or continuous thermodilution, and was equally repeatable compared with R

Indexed as

Coronary CirculationHeart TransplantationVascular ResistanceAdultFemaleHumansMaleMicrocirculationMiddle AgedThermodilutioncoronary artery diseaseheart transplantationhyperemiaphysiologythermodilution

Identifiers

PMID40233166
PMCPMC12001742

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.