ArticleBMC public health2025
Cardiometabolic index is negatively associated with the risk of sarcopenia in the middle aged and elderly Chinese: the first longitudinal evidence from CHARLS.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Depression and risk of incident heart diseases among older adults at CKM stages 0-3: evidence from the China Health and Retirement Longitudinal Study.Annals of medicine · 2026Article
- Higher cardiometabolic index elevates the risk of hyperuricemia in the elderly: findings from the China health and retirement longitudinal study.Annals of medicine · 2025Article
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5 authors.
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Abstract
backgroundThe association between sarcopenia and cardiometabolic index (CMI) among the Chinese elderly adults remains unclear. The present study aimed to examine the association based on a national survey.
methodsData from China Health and Retirement Longitudinal Study (CHARLS, wave 2011 and 2015) were employed. All subjects met the inclusion criteria were classified by the median of CMI. Four logistic regression models were established to explore the cross-sectional and longitudinal associations between CMI and sarcopenia. Subgroups analysis, tendency analysis, etc. were conducted to testify the robustness of the association. The non-linear relationship was explored using restricted cubic spline (RCS).
results5,016 participants were enrolled in this study. The ORs of the longitudinal analysis in the models were 0.42(0.34,0.53), 0.37(0.29,0.46), 0.40(0.31,0.51) and 0.42(0.33,0.53)), respectively. Similar results were also found after propensity score matching (PSM), inverse probability weighting (IPTW) and cross-sectional analysis. Moreover, a non-linear relationship was found between CMI and sarcopenia in the total participants (both p for overall and p for non-linear < 0.001).
conclusionA U-shaped relationship between CMI and sarcopenia risk was found in the middle aged and elderly Chinese, with both deficient and excessive CMI levels showing detrimental effects. Maintaining a moderate CMI significantly diminishes the risk of sarcopenia.
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