Evidence map›Paper›PMID 40235311›Full record

ReviewChannels (Austin, Tex.)2025

The GluN3-containing NMDA receptors.

Kunlong Xiong, Shulei Lou, Zuoyu Lian, Yunlin Wu, Zengwei Kou

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Channels (Austin, Tex.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Inactivation of NMDAR and CaMKII signaling within the prelimbic cortex blocks incubated cocaine- and sucrose-craving.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kunlong XiongDepartment of Pulmonary and Critical Care Medicine, Affiliated First Hospital of Ningbo University, Ningbo, Zhejiang, China.
Shulei LouInstitute of Hospital Management, Linyi People's Hospital, Linyi, Shandong, China.
Zuoyu LianDepartment of General Practice, Cicheng Town Central Health Center, Ningbo, Zhejiang, China.
Yunlin WuHospital Infection Control Section, Affiliated First Hospital of Ningbo University, Ningbo, Zhejiang, China.
Zengwei KouDepartment of Laboratory Medicine and Pathobiology, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.ORCID 0009-0004-8779-7186

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N-methyl-D-aspartate receptors (NMDARs) are heterotetrameric ion channels that play crucial roles in brain function. Among all the NMDAR subtypes, GluN1-N3 receptors exhibit unique agonist binding and gating properties. Unlike "conventional" GluN1-N2 receptors, which require both glycine and glutamate for activation, GluN1-N3 receptors are activated solely by glycine. Furthermore, GluN1-N3 receptors display faster desensitization, reduced Ca

Indexed as

Receptors, N-Methyl-D-AspartateAnimalsBrainHumansReceptors, N-Methyl-D-AspartateIonotropic glutamate receptorsligand-gated ion channelspathology and physiologyprotein predictionsynaptic transmission

Identifiers

PMID40235311
PMCPMC12005412

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.