ArticleQuantitative imaging in medicine and surgery2025
Diagnostic potential of pericoronary adipose tissue mean attenuation for coronary atherosclerotic heart disease: a comparative analysis with the fat attenuation index.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The fat attenuation index (FAI), a threshold-based method for assessing pericoronary adipose tissue (PCAT) density, provides strong evidence for patient-specific coronary inflammation assessment. However, the reliance on fat thresholds may result in the omission of some critical information. Thus, this study aimed to explore the diagnostic potential of a novel method, pericoronary adipose tissue mean attenuation (PCAT Methods: This single-center observational study enrolled patients undergoing coronary computed tomography angiography (CCTA) between May 2021 and October 2022. In total, 75 patients with plaque and 63 patients without plaque were enrolled in the study. PCAT density was measured at various distances (0.50, 0.75, 1.00, 1.25, 1.50, 1.75, and 2.00 mm) from the vascular wall in the non-plaque group to investigate the effect of varying distances from the coronary artery on PCAT density. A Bland-Altman analysis and intraclass correlation coefficients were used to assess the feasibility and reproducibility of the PCAT Results: As the distance from the lumen increased, the PCAT density gradually decreased, plateauing after a distance of 0.75 mm (P=0.907). There were no differences between PCAT Conclusions: The novel PCAT
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