Evidence map›Paper›PMID 40236209›Full record

ArticlebioRxiv : the preprint server for biology2025

Genome-directed study reveals the diversity of

Gianlucca G Nicastro, Stephanie Sibinelli-Sousa, Julia Takuno Hespanhol, Thomas W C Santos, Joseph P Munoz, Rosangela S Santos, Blanca M Perez-Sepulveda, Sayuri Miyamoto, L Aravind, Robson F de Souza and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Gianlucca G NicastroDepartamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0002-3133-2441
Stephanie Sibinelli-SousaDepartment of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, USA.ORCID 0000-0003-4875-8737
Julia Takuno HespanholDepartment of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, USA.ORCID 0000-0001-6701-7286
Thomas W C SantosDepartamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
Joseph P MunozDepartment of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, USA.
Rosangela S SantosDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.
Blanca M Perez-SepulvedaInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.ORCID 0000-0002-2891-4010
Sayuri MiyamotoDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0002-5714-8984
L AravindComputational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, USA.ORCID 0000-0003-0771-253X
Robson F de SouzaDepartamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0002-5284-4630
Ethel Bayer-SantosDepartment of Molecular Biosciences, College of Natural Sciences, The University of Texas at Austin, Austin, USA.ORCID 0000-0003-3832-3449

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial warfare is a common and ancient phenomenon in nature, where bacterial species use strategies to inhibit the growth or kill competitors. This involves the production and deployment of antibacterial toxins that disrupt essential cellular processes in target cells. The continuous arms race in which bacteria acquire new toxin and immunity proteins to promote increased adaptation to their environment is responsible for the diversification of this toxin repertoire. Here, we deployed

Indexed as

acyltransferaseeffectorNlpC/P60phospholipaseSalmonellaT6SStoxin

Identifiers

PMID40236209
PMCPMC11996579

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.