Evidence map›Paper›PMID 40238945›Full record

ArticleAmerican journal of respiratory and critical care medicine2025

Associations of Prepandemic Lung Function and Structure with COVID-19 Outcomes: The C4R Study.

Pallavi P Balte, John S Kim, Yifei Sun, Nori Allen, Elsa Angelini, Alexander Arynchyn, R Graham Barr, Michael Blaha, Russell Bowler, Jeff Carr and 43 more

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Loss of Lung Function Led to Loss of Life during the COVID-19 Pandemic.American journal of respiratory and critical care medicine · 2025
    Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

53 authors.

Pallavi P BalteDivision of General Medicine, Department of Medicine.ORCID 0000-0001-5610-3744
John S KimDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia.
Yifei SunDepartment of Biostatistics, Mailman School of Public Health, and.
Nori AllenCenter for Epidemiology and Population Health, Northwestern Feinberg School of Medicine, Chicago, Illinois.
Elsa AngeliniDepartment of Biomedical Engineering, Columbia University, New York, New York.
Alexander ArynchynDivision of Preventive Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
R Graham BarrDivision of General Medicine, Department of Medicine.
Michael BlahaDepartment of Medicine, and.
Russell BowlerDivision of Pulmonary, Critical Care, and Sleep Medicine, and.ORCID 0000-0003-4651-363X
Jeff CarrDepartment of Biomedical Informatics, Vanderbilt University Medical University, Nashville, Tennessee.
Shelley A ColeTexas Biomedical Research Institute, San Antonio, Texas.
David CouperCollaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Ryan T DemmerDivision of Epidemiology, Department of Quantitative Health Sciences, College of Medicine and Science, Mayo Clinic, Rochester, Minnesota.
Margaret DoyleDepartment of Pathology and Laboratory Medicine, University of Vermont, Burlington, Vermont.
Mitchell ElkindDepartment of Neurology, Columbia University Irving Medical Center, New York, New York.
Raúl San José EstéparDepartment of Radiology and.ORCID 0000-0002-3677-1996
Olga Garcia-BedoyaDivision of Academic Internal Medicine and Geriatrics and.
Suresh GarudadriDivision of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco, San Francisco, California.
Nadia N HanselDepartment of Medicine, and.
Emilia A HermannDivision of General Medicine, Department of Medicine.
Eric A HoffmanDepartment of Radiology.ORCID 0000-0001-8456-9437
Stephen M HumphriesDepartment of Radiology, National Jewish Health, Denver, Colorado.ORCID 0000-0002-5113-4530
Gary M HunninghakeDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Robert KaplanDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York.
Jerry A KrishnanDivision of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois, Chicago, Illinois.ORCID 0000-0001-5525-4778
Andrew LaineDepartment of Biomedical Engineering, Columbia University, New York, New York.
Joyce S LeeDivision of Pulmonary and Critical Care, Department of Medicine, University of Colorado, Aurora, Colorado.
David A LynchDepartment of Radiology, National Jewish Health, Denver, Colorado.
Barry MakeDivision of Pulmonary, Critical Care, and Sleep Medicine, and.
Kunihiro MatsushitaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Will McKleroyKaiser Permanente San Francisco Medical Center, San Francisco, California.
Yuan-I MinDepartment of Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
Sneha N NaikDepartment of Biomedical Engineering, Columbia University, New York, New York.
George O'ConnorPulmonary, Allergy, Sleep, and Critical Care Medicine and.
Olivia O'DriscollDepartment of Biomedical Engineering, Columbia University, New York, New York.
Eyal OrenDivision of Epidemiology and Biostatistics, School of Public Health, San Diego State University, San Diego, California.
Anna J PodolanczukDivision of Pulmonary and Critical Care Medicine, Weill Cornell Medicine, New York, New York.ORCID 0000-0002-9559-1485
Wendy S PostDivision of Cardiology, Departments of Medicine and Epidemiology, Johns Hopkins University, Baltimore, Maryland.
Tess PottingerDivision of General Medicine, Department of Medicine.
Elizabeth ReganDivision of Rheumatology, Department of Medicine, and.
Annie RuskDivision of Respiratory Medicine, Department of Internal Medicine, Mayo Clinic, Scottsdale, Arizona.
Mary SalvatoreDepartment of Radiology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York.
David A SchwartzDivision of Pulmonary and Critical Care, Department of Medicine, University of Colorado, Aurora, Colorado.
Benjamin SmithDivision of General Medicine, Department of Medicine.
Daniela Sotres-AlvarezCollaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Jason G UmansMedStar Health Research Institute, School of Medicine, Georgetown University, Washington, DC.
Ramachandran S VasanSchool of Public Health, University of Texas School of Public Health San Antonio, San Antonio, Texas.
George WashkoDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Sally WenzelDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania; and.ORCID 0000-0002-4242-0164
Prescott WoodruffDivision of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco, San Francisco, California.
Vanessa XanthakisSection of Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.
Victor E OrtegaDivision of Respiratory Medicine, Department of Internal Medicine, Mayo Clinic, Scottsdale, Arizona.
Elizabeth C OelsnerDivision of General Medicine, Department of Medicine.

Funding

ACTIV Integration of Host-targeting Therapies for COVID-19 Administrative Coordinating CenterOT2HL156812 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI NOLEN, TRACY L, THOMAS, SONIA M · 2020 to 2024
$1270.7M
The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
ARIC Neurocognitive Study (ARIC-NCS) Renewal 2023-2028U01HL096812 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI JOSEF CORESH, THOMAS H MOSLEY · 2010 to 2026
$65.7M
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5M
Subclinical Vascular Contributions to Alzheimer's Disease: The Multi-Ethnic Study of Atherosclerosis (MESA) Multisite Study of AD (Renewal)R01AG058969 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Timothy M. Hughes, YONGMEI LIU · 2018 to 2026
$33.4M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
FRAMINGHAM HEART STUDY - YEAR 5 EXAM75N92019D00031 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI RAMACHANDRAN, VASAN · 2019 to 2024
$29.8M
SPIROMICS II: Biological underpinnings of COPD heterogeneity and progressionU01HL137880 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WOODRUFF, PRESCOTT G · 2017 to 2021
$27.9M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Mechanisms of Familial Pulmonary FibrosisP01HL092870 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SCHWARTZ, DAVID ALBERT · 2010 to 2020
$21.6M
Intramural NIH HHS Z01 ES101947NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NCATS NIH HHS UL1 TR001420NHLBI NIH HHS 75N92019D00027NHLBI NIH HHS 75N92019D00028NHLBI NIH HHS 75N92019D00029NHLBI NIH HHS 75N92019D00030NHLBI NIH HHS 75N92019D00031NHLBI NIH HHS 75N92020D00001NHLBI NIH HHS 75N92020D00002NHLBI NIH HHS 75N92020D00003NHLBI NIH HHS 75N92020D00004NHLBI NIH HHS 75N92020D00005NHLBI NIH HHS 75N92020D00006NHLBI NIH HHS 75N92020D00007NHLBI NIH HHS 75N92022D00001NHLBI NIH HHS 75N92022D00002NHLBI NIH HHS 75N92022D00003NHLBI NIH HHS 75N92022D00004NHLBI NIH HHS 75N92022D00005NHLBI NIH HHS 75N92023D00002NHLBI NIH HHS 75N92023D00003NHLBI NIH HHS 75N92023D00004NHLBI NIH HHS 75N92023D00005NHLBI NIH HHS 75N92023D00006NHLBI NIH HHS HHSN268200900013CNHLBI NIH HHS HHSN268200900014CNHLBI NIH HHS HHSN268200900015CNHLBI NIH HHS HHSN268200900016CNHLBI NIH HHS HHSN268200900017CNHLBI NIH HHS HHSN268200900018CNHLBI NIH HHS HHSN268200900019CNHLBI NIH HHS HHSN268200900020CNHLBI NIH HHS HHSN268201500001CNHLBI NIH HHS HHSN268201500001INHLBI NIH HHS HHSN268201500003CNHLBI NIH HHS HHSN268201500003INHLBI NIH HHS HHSN268201800010INHLBI NIH HHS HHSN268201800011CNHLBI NIH HHS HHSN268201800011INHLBI NIH HHS HHSN268201800012CNHLBI NIH HHS HHSN268201800012INHLBI NIH HHS HHSN268201800014CNHLBI NIH HHS HHSN268201800014INHLBI NIH HHS HHSN268201800015INHLBI NIH HHS K23 HL130627NHLBI NIH HHS K23 HL140199NHLBI NIH HHS N01 HC025195NHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS OT2 HL156812NHLBI NIH HHS P01 HL092870NHLBI NIH HHS R01 HL077612NHLBI NIH HHS R01 HL093081NHLBI NIH HHS R01 HL095393NHLBI NIH HHS R01 HL097163NHLBI NIH HHS R01 HL098433NHLBI NIH HHS R01 HL101250NHLBI NIH HHS R01 HL109282NHLBI NIH HHS R01 HL109284NHLBI NIH HHS R01 HL109301NHLBI NIH HHS R01 HL109315NHLBI NIH HHS R01 HL109319NHLBI NIH HHS R01 HL121700NHLBI NIH HHS R01 HL127028NHLBI NIH HHS R01 HL127659NHLBI NIH HHS R01 HL130506NHLBI NIH HHS R01 HL135009NHLBI NIH HHS R01 HL157634NHLBI NIH HHS R21 HL120770NHLBI NIH HHS R21 HL121457NHLBI NIH HHS R21 HL129924NHLBI NIH HHS R21 HL153700NHLBI NIH HHS R21 HL165405NHLBI NIH HHS R33 HL120770NHLBI NIH HHS U01 HL041642NHLBI NIH HHS U01 HL041652NHLBI NIH HHS U01 HL041654NHLBI NIH HHS U01 HL065520NHLBI NIH HHS U01 HL065521NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897NHLBI NIH HHS U01 HL096812NHLBI NIH HHS U01 HL096814NHLBI NIH HHS U01 HL096899NHLBI NIH HHS U01 HL096902NHLBI NIH HHS U01 HL096917NHLBI NIH HHS U01 HL137880NHLBI NIH HHS U10 HL109086NHLBI NIH HHS U10 HL109146NHLBI NIH HHS U10 HL109152NHLBI NIH HHS U10 HL109164NHLBI NIH HHS U10 HL109168NHLBI NIH HHS U10 HL109172NHLBI NIH HHS U10 HL109250NHLBI NIH HHS U10 HL109257NHLBI NIH HHS U24 HL141762NHLBI NIH HHS UG3 HL151865NHLBI NIH HHS UH2 HL123442NHLBI NIH HHS UH3 HL123442NIA NIH HHS R01 AG058969NIEHS NIH HHS P30 ES005605NIH HHS P51 OD011133NIMHD NIH HHS HHSN268201800013ININDS NIH HHS R01 NS102715
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19LungAgedFemaleForced Expiratory VolumeHumansMaleMiddle AgedProspective StudiesPulmonary EmphysemaRisk FactorsSARS-CoV-2SpirometryTomography, X-Ray ComputedUnited StatesCOVID-19lung function and structureobstructive physiologypercentage emphysemarestrictive physiology

Identifiers

PMID40238945
PMCPMC12264703

What Socratic holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.