Evidence map›Paper›PMID 40243573›Full record

ArticleInternational journal of molecular sciences2025

Characterization of Gut Microbiota in Patients with Active Spreading Vitiligo Based on Whole-Genome Shotgun Sequencing.

Hyun Jeong Ju, Woo Hyun Song, Ji Hae Shin, Ji Hae Lee, Jung Min Bae, Young Bok Lee, Minho Lee

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hyun Jeong JuDepartment of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul 16247, Republic of Korea.ORCID 0000-0003-2711-3112
Woo Hyun SongDepartment of Life Science, Dongguk University-Seoul, Goyang 10326, Republic of Korea.
Ji Hae ShinDepartment of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul 16247, Republic of Korea.ORCID 0009-0001-8158-1884
Ji Hae LeeDepartment of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul 16247, Republic of Korea.ORCID 0000-0002-5132-1627
Jung Min BaeDepartment of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul 16247, Republic of Korea.
Young Bok LeeDepartment of Dermatology, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, Seoul 11765, Republic of Korea.ORCID 0000-0002-8642-2479
Minho LeeDepartment of Life Science, Dongguk University-Seoul, Goyang 10326, Republic of Korea.ORCID 0000-0002-0168-9546

Funding

Amorepacific research fund 2024National Research Foundation of Korea NRF 2017R1A5A2015369
6 · The paper itself

Abstract

Vitiligo is an autoimmune skin disease with a significant psychological burden and complex pathogenesis. While genetic factors contribute approximately 30% to its development, recent evidence suggests a crucial role of the gut microbiome in autoimmune diseases. This study investigated differences in gut microbiome composition and metabolic pathways between active spreading vitiligo patients and healthy controls using shotgun whole-genome sequencing in a Korean cohort. Taxonomic profiling reveals distinct characteristics in microbial community structure, with vitiligo patients showing an imbalanced proportion dominated by Actinomycetota and Bacteroidota. The vitiligo group exhibited significantly reduced abundance of specific species including

Indexed as

Gastrointestinal MicrobiomeVitiligoWhole Genome SequencingAdultFemaleHumansMaleMetabolic Networks and PathwaysMiddle AgedShotgun Sequencingautoimmunedysbiosisgut microbiomemetabolic pathwaysshotgun sequencingvitiligo

Identifiers

PMID40243573
PMCPMC11988336

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.