Evidence map›Paper›PMID 40243577›Full record

ArticleInternational journal of molecular sciences2025

Potential Role of

Martina Paradzik Simunovic, Marina Degoricija, Jelena Korac-Prlic, Mladen Lesin, Robert Stanic, Livia Puljak, Ivana Olujic, Josipa Marin Lovric, Ana Vucinovic, Zana Ljubic and 5 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Martina Paradzik SimunovicDepartment of Ophthalmology, University Hospital of Split, Spinciceva 1, 21000 Split, Croatia.ORCID 0000-0002-0735-5598
Marina DegoricijaLaboratory for Cancer Research, School of Medicine, University of Split, Soltanska 2, 21000 Split, Croatia.ORCID 0000-0001-7023-9381
Jelena Korac-PrlicLaboratory for Cancer Research, School of Medicine, University of Split, Soltanska 2, 21000 Split, Croatia.ORCID 0000-0002-7840-9979
Mladen LesinDepartment of Ophthalmology, University Hospital of Split, Spinciceva 1, 21000 Split, Croatia.
Robert StanicDepartment of Ophthalmology, University Hospital of Split, Spinciceva 1, 21000 Split, Croatia.
Livia PuljakCenter for Evidence-Based Medicine and Healthcare, Catholic University of Croatia, 10000 Zagreb, Croatia.ORCID 0000-0002-8467-6061
Ivana OlujicDepartment of Ophthalmology, University Hospital of Split, Spinciceva 1, 21000 Split, Croatia.
Josipa Marin LovricDepartment of Ophthalmology, University Hospital of Split, Spinciceva 1, 21000 Split, Croatia.
Ana VucinovicDepartment of Ophthalmology, University Hospital of Split, Spinciceva 1, 21000 Split, Croatia.
Zana LjubicDepartment of Ophthalmology, University Hospital of Split, Spinciceva 1, 21000 Split, Croatia.
James ThissenBiosciences and Biotechnology Division, Lawrence Livermore National Laboratory, Livermore, CA 94550, USA.
Car Reen KokBiosciences and Biotechnology Division, Lawrence Livermore National Laboratory, Livermore, CA 94550, USA.ORCID 0009-0001-1131-9784
Crystal JaingBiosciences and Biotechnology Division, Lawrence Livermore National Laboratory, Livermore, CA 94550, USA.
Kajo BucanDepartment of Ophthalmology, University Hospital of Split, Spinciceva 1, 21000 Split, Croatia.
Janos TerzicLaboratory for Cancer Research, School of Medicine, University of Split, Soltanska 2, 21000 Split, Croatia.

Funding

Croatian Science Foundation IP-2020-02-8921
6 · The paper itself

Abstract

Pterygium is a condition affecting the ocular surface, marked by a triangular-shaped growth of fibrotic tissue extending from the nasal conjunctiva toward the corneal center, potentially causing visual impairment. While ultraviolet (UV )light exposure is the primary risk factor for pterygium, its underlying cause remains unclear. In order to better understand the true genesis of pterygium development, we investigated pterygium tissue and compared it with healthy conjunctiva controls. Given the eye's direct environmental exposure, we analyzed the microbiota composition using metagenomic sequencing of pterygium tissue to identify microbes potentially associated with this condition. Metagenomic sequencing revealed a higher prevalence of the fungus

Indexed as

MalasseziaPterygiumAgedConjunctivaFemaleGene Expression ProfilingHumansMaleMicrobiotaMiddle AgedCHIT1 geneMalassezia restrictaocular microbiomepterygium

Identifiers

PMID40243577
PMCPMC11989039

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.