ReviewInternational journal of molecular sciences2025
A Comprehensive Overview of Stress, Resilience, and Neuroplasticity Mechanisms.
Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- An Overview of Stress Analysis Based on Physiological Signals: Systematic Review of Open Datasets and Current Trends.Sensors (Basel, Switzerland) · 2025Pooled it
- War trauma and psychomotor developmental disorders in children aged 6-12 in Lubumbashi: a comparative study.European journal of psychotraumatology · 2026Article
- Stress induced hyperphagia iniScience · 2026Article
- Exercise-induced neuropeptidergic and neurochemical neuroadaptation in stress regulation and emotional disorders.Acta neurologica Belgica · 2026Review
- Article
- Immature Neurons in the Postnatal Brain: Markers, Modulation, and Involvement in Normal and Aberrant Plasticity.International journal of molecular sciences · 2026Review
- Interplay of Vitamin D3, Wnt/β-Catenin Pathway, and Oxidative DNA Injury in CMS-Induced Depression Model.Biomedicines · 2026Article
- Sex-dependent effects of environmental enrichment on mood-related behaviors, central and peripheral BDNF, and adrenal catecholamine enzymes in mice.Physiological reports · 2026Article
- Combined Bacopa, Phosphatidylserine, and Choline Protect Against Stress-Induced Neurotoxicity.Biomedicines · 2026Article
- Symptoms of Depression, Anxiety, and Stress Among Nursing Students and Coping Strategies Used.Revista brasileira de enfermagem · 2026Observational
- The sports-education-health nexus: assessing psychological, cognitive, and social outcomes in a public health framework.Frontiers in public health · 2026Article
- Baseline PTSD and depressive symptoms predict multidimensional recovery after combat-related transtibial amputation: a prospective cohort study.Frontiers in rehabilitation sciences · 2026Article
- Nutritional timing and stress biology: intermittent fasting as a hormetic signal for adaptation.Frontiers in nutrition · 2026Review
- Can symptom-severity phenotypes identify depression risk after mild traumatic brain injury? A cluster-based approach.BMC psychiatry · 2025Article
- The Role of Tenascin-C in Neuroinflammation and Neuroplasticity.International journal of molecular sciences · 2025Review
- Combined nicotinamide riboside and magnesium-l-theanine protects against chronic stress-induced gut-liver injury by modulating NAD⁺ and metabolic pathways.Molecular biology reports · 2025Article
- Entangled Autopoiesis: Reframing Psychotherapy and Neuroscience Through Cognitive Science and Systems Engineering.Brain sciences · 2025Review
- Mapping the Relationship Between Post-Traumatic Stress and Post-Traumatic Growth and the Mediating Role of Resilience.Clinical psychology & psychotherapyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Stress is a core concept in the mental health field that expands upon the seminal definition of stress as an acute response to the disruption of homeostasis. Stress is a complex process that involves both environmental challenges and the triggering of internal responses and impacts physiological, psychological, and behavioral systems. The capacity of the human brain to cope with stress is particularly crucial in early life, when neurodevelopment is highly plastic. Early-life stress (ELS), defined as exposure to severe chronic stress during sensitive periods of development, has been shown to cause lasting changes in brain structure and function. However, not all individuals exposed to ELS develop pathological outcomes, suggesting the presence of resilience mechanisms: adaptive processes that allow an individual to cope with adverse situations while maintaining psychological and neurobiological health. The aim of this review was to synthesize recent advances in the understanding of the neuroplasticity mechanisms underlying resilience to ELS. We discussed the neurobiological pathways implicated in stress response and adaptation, including the roles of neurogenesis, synaptic plasticity, and neural circuit remodeling. By focusing on the interplay between stress-induced neuroplastic changes and resilience mechanisms, we aimed to provide insights into potential therapeutic targets for stress-related psychopathology.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.