In one paragraphArticle in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
9 authors.
Giulia BernardiniONE-HEALTH Lab, Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro, 53100 Siena, Italy.ORCID 0000-0003-0016-0728 Alfonso TrezzaONE-HEALTH Lab, Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro, 53100 Siena, Italy.
Elena PetricciONE-HEALTH Lab, Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro, 53100 Siena, Italy.ORCID 0000-0002-9685-6342 Giulia RomagnoliONE-HEALTH Lab, Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro, 53100 Siena, Italy.ORCID 0000-0002-8419-5284 Demetra ZambardinoONE-HEALTH Lab, Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro, 53100 Siena, Italy.ORCID 0009-0007-7645-1157 Fabrizio ManettiONE-HEALTH Lab, Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro, 53100 Siena, Italy.ORCID 0000-0002-9598-2339 Daniela BraconiONE-HEALTH Lab, Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro, 53100 Siena, Italy.ORCID 0000-0002-9657-4169 Michela GeminianiONE-HEALTH Lab, Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro, 53100 Siena, Italy.ORCID 0000-0002-6910-0056 Annalisa SantucciONE-HEALTH Lab, Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro, 53100 Siena, Italy.ORCID 0000-0001-6976-9086 Funding
Ministero dello Sviluppo Economico (MISE) SNIHTT DR n. 2137/2020 del 22.12.2020
6 · The paper itselfAbstract
Alkaptonuria (AKU) is an ultra-rare genetic disorder caused by mutations in the homogentisate 1,2-dioxygenase (
Indexed as
4-Hydroxyphenylpyruvate DioxygenaseAlkaptonuriaEnzyme InhibitorsComputer SimulationCyclohexanonesHomogentisic AcidHumansMolecular Docking SimulationNitrobenzoates4-Hydroxyphenylpyruvate DioxygenaseCyclohexanonesEnzyme InhibitorsHomogentisic AcidnitisinoneNitrobenzoates4-HPPDAKUdocking simulationIC50IC90inhibitorsmolecular dynamics simulationmolecular modelingNTBCresidence timesteered molecular dynamics (SMD)
Identifiers
PMID40243989
PMCPMC11988800
What Socratic holds
Textmetadata
LicenceCC BY
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