Evidence map›Paper›PMID 40244042›Full record

ArticleInternational journal of molecular sciences2025

The Leucine-Rich Repeat Kinase 2 Variant LRRK2

Alejandro Sandoval, Alejandra Corzo-López, Paz Duran, Diana Tovar-Soto, Bryan Vargas-Caballero, Valeria Galicia-Saldaña, Ricardo González-Ramírez, Ricardo Felix

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alejandro SandovalSchool of Medicine FES Iztacala, National Autonomous University of Mexico (UNAM), Tlalnepantla 54090, Mexico.
Alejandra Corzo-LópezSchool of Medicine FES Iztacala, National Autonomous University of Mexico (UNAM), Tlalnepantla 54090, Mexico.
Paz DuranDepartment of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010, USA.ORCID 0000-0001-8729-8636
Diana Tovar-SotoSchool of Medicine FES Iztacala, National Autonomous University of Mexico (UNAM), Tlalnepantla 54090, Mexico.
Bryan Vargas-CaballeroDepartment of Cell Biology, Centre for Research and Advanced Studies (Cinvestav), Mexico City 077360, Mexico.
Valeria Galicia-SaldañaSchool of Medicine FES Iztacala, National Autonomous University of Mexico (UNAM), Tlalnepantla 54090, Mexico.
Ricardo González-RamírezDepartment of Molecular Biology and Histocaompatibility, "Dr. Manuel Gea González" General Hospital, Mexico City 14080, Mexico.ORCID 0000-0003-1399-8036
Ricardo FelixDepartment of Cell Biology, Centre for Research and Advanced Studies (Cinvestav), Mexico City 077360, Mexico.ORCID 0000-0002-5383-7176

Funding

PAPIIT-UNAM IN211524SECTEI (MEXICO) SECTEI/146/2024
6 · The paper itself

Abstract

Voltage-gated Ca

Indexed as

Calcium Channels, L-TypeLeucine-Rich Repeat Serine-Threonine Protein Kinase-2Parkinson DiseaseHEK293 CellsHumansMutationPhosphorylationUp-RegulationCalcium Channels, L-TypeLeucine-Rich Repeat Serine-Threonine Protein Kinase-2LRRK2 protein, humancalcium channelsCav1.3LRRK2Parkinson’s disease

Identifiers

PMID40244042
PMCPMC11989569

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.