Asymmetric Dimethylaminohydrolase Gene Polymorphisms Associated with Preeclampsia Comorbid with HIV Infection in Pregnant Women of African Ancestry.

Mbuso Herald Mthembu, Samukelisiwe Sibiya, Zinhle Pretty Mlambo, Nompumelelo P Mkhwanazi, Thajasvarie Naicker

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mbuso Herald MthembuDepartment of Obstetrics and Gynaecology, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban 4041, South Africa.ORCID 0000-0001-9956-0726

Samukelisiwe SibiyaHIV Pathogenesis Programme, Doris Duke Medical Research Institute, College of Health Sciences, University of KwaZulu-Natal, Durban 4041, South Africa.

Zinhle Pretty MlamboOptics and Imaging Centre, Doris Duke Medical Research Institute, College of Health Sciences, University of KwaZulu-Natal, Durban 4041, South Africa.

Nompumelelo P MkhwanaziHIV Pathogenesis Programme, Doris Duke Medical Research Institute, College of Health Sciences, University of KwaZulu-Natal, Durban 4041, South Africa.ORCID 0000-0002-0808-9201

Thajasvarie NaickerOptics and Imaging Centre, Doris Duke Medical Research Institute, College of Health Sciences, University of KwaZulu-Natal, Durban 4041, South Africa.ORCID 0000-0001-6917-2191

Funding

Professor Thajasvarie Naicker Productivity fundUniversity of KwaZulu-Natal College of Health Sciences 214556782

6 · The paper itself

Abstract

Asymmetric dimethylarginine (ADMA) is an endogenous nitric oxide synthase (NOS) inhibitor associated with vascular disease, which is prevalent in human plasma. Two isoforms of the enzyme dimethylarginine dimethylaminohydrolase (DDAH), DDAH 1 and 2, degrade ADMA. This study investigates the association of

Indexed as

AmidohydrolasesBlack PeopleHIV InfectionsPolymorphism, Single NucleotidePre-EclampsiaAdultComorbidityFemaleGenetic Predisposition to DiseaseHumansPregnancyYoung AdultAmidohydrolasesdimethylargininaseADMADDAHendothelial impairmentHIV infectionpreeclampsiasingle-nucleotide polymorphisms

Identifiers

PMID40244094

DOI10.3390/ijms26073271

PMCPMC11989882

What Socratic holds

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LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.