Evidence mapPaperPMID 40244271Full record

ReviewInternational journal of molecular sciences2025

Myocardial Revascularization in Patients with Diabetes and Heart Failure-A Narrative Review.

Stefan Zivkovic, Aleksandar Mandic, Kosta Krupnikovic, Aleksa Obradovic, Vojko Misevic, Mihajlo Farkic, Ivan Ilic, Milorad Tesic, Srdjan Aleksandric, Stefan Juricic and 2 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Stefan ZivkovicCardiology Clinic, Institute for Cardiovascular Diseases "Dedinje", 11000 Belgrade, Serbia.ORCID 0000-0002-3952-4560
Aleksandar MandicCardiology Clinic, Institute for Cardiovascular Diseases "Dedinje", 11000 Belgrade, Serbia.
Kosta KrupnikovicCardiology Clinic, Institute for Cardiovascular Diseases "Dedinje", 11000 Belgrade, Serbia.ORCID 0009-0002-7886-6763
Aleksa ObradovicCardiology Clinic, Institute for Cardiovascular Diseases "Dedinje", 11000 Belgrade, Serbia.ORCID 0009-0006-2509-9782
Vojko MisevicCardiology Clinic, Institute for Cardiovascular Diseases "Dedinje", 11000 Belgrade, Serbia.
Mihajlo FarkicCardiology Clinic, Institute for Cardiovascular Diseases "Dedinje", 11000 Belgrade, Serbia.
Ivan IlicCardiology Clinic, Institute for Cardiovascular Diseases "Dedinje", 11000 Belgrade, Serbia.ORCID 0000-0002-5110-7102
Milorad TesicFaculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0002-3758-3719
Srdjan AleksandricFaculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0001-6903-4477
Stefan JuricicCardiology Clinic, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Branko BeleslinFaculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0001-9452-8241
Milan DobricCardiology Clinic, Institute for Cardiovascular Diseases "Dedinje", 11000 Belgrade, Serbia.ORCID 0000-0001-7643-0451

Funding

Ministry of Science, Techhnological Developement, and Innovation of the Republic of Serbia 451-03-65/2024-03/200110
6 · The paper itself

Abstract

Heart failure and diabetes mellitus are major contributors to global morbidity and mortality, with their prevalence continuously rising, primarily due to aging populations and improvements in healthcare. These conditions often coexist or develop sequentially, leading to complex interactions that significantly influence the progression and management of both diseases. Furthermore, heart failure and diabetes are commonly associated with coronary artery disease, which presents a unique challenge in clinical management, particularly in the context of myocardial revascularization. The presence of diabetes exacerbates atherosclerotic progression and impairs endothelial function, while heart failure complicates the perfusion and recovery of myocardial tissue post-intervention. This narrative review delves into the underlying mechanisms contributing to revascularization failure in patients with heart failure and diabetes, emphasizing the importance of understanding these interactions for optimal treatment. The review also summarizes key findings from randomized controlled trials, examining evidence both in the general population and in specific subgroups, including the elderly and patients with left main coronary artery disease, chronic kidney disease, peripheral artery disease, and chronic obstructive pulmonary disease. Understanding these complexities is critical for improving patient outcomes.

Indexed as

Diabetes MellitusHeart FailureMyocardial RevascularizationCoronary Artery DiseaseHumanscoronary artery diseasediabetes mellitusheart failuremyocardial revascularization

Identifiers

PMID40244271
PMCPMC11989545

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.