Evidence map›Paper›PMID 40244306›Full record

ReviewAging clinical and experimental research2025

Aging, longevity, and healthy aging: the public health approach.

Vincenza Gianfredi, Daniele Nucci, Flavia Pennisi, Stefania Maggi, Nicola Veronese, Pinar Soysal

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Aging clinical and experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
127citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

127 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  20. Let's Rethink Aging.Delaware journal of public health · 2026
    Article

67 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vincenza GianfrediDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy. vincenza.gianfredi@unimi.it.ORCID https://orcid.org/0000-0003-3848-981X
Daniele NucciStruttura Semplice Dipartimentale Igiene Alimenti e Nutrizione, Dipartimento di Igiene e Prevenzione Sanitaria, Agenzia di Tutela della Salute (ATS) Brescia, Viale Duca degli Abruzzi, 15, Brescia, 20124, Italy.ORCID https://orcid.org/0000-0003-4546-213X
Flavia PennisiNational PhD Programme in One Health Approaches to Infectious Diseases and Life Science Research, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, 27100, Italy.ORCID https://orcid.org/0009-0001-9185-9747
Stefania MaggiConsiglio Nazionale delle Ricerche, Neuroscience Institute, Padova, Italy.ORCID https://orcid.org/0000-0002-0453-8663
Nicola VeroneseSaint Camillus International University of Health Sciences, Rome, Italy.ORCID https://orcid.org/0000-0002-9328-289X
Pinar SoysalDepartment of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.ORCID https://orcid.org/0000-0002-6042-1718

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPopulation aging is one of the most significant global demographic changes of the 21st century, driven by increased life expectancy and declining fertility rates. This phenomenon presents both achievements and challenges for public health systems worldwide.

aimsOn the one hand, advances in healthcare and socio-economic conditions have contributed to longer lives and improved quality of life for older adults. On the other hand, aging populations are increasingly affected by chronic diseases, greriatric syndromes, and multimorbidity, leading to greater healthcare demands and higher associated costs.

methodsThis manuscript explores evidence on regards of the impact of aging on healthcare and economic systems, emphasizing the need for a paradigm shift toward healthy aging.

resultsHealthy aging, as defined by the World Health Organization, focuses on the maintenance of intrinsic capacity, physical, mental, and social well-being throughout life. It highlights the importance of preventive healthcare, proper nutrition, and regular physical activity in delaying the onset of chronic conditions and maintaining functional independence. Furthermore, the manuscript addresses the challenges faced by healthcare infrastructures and pension systems as they adapt to aging populations, with particular attention to the strain caused by workforce shortages and the rising need for long-term care. DISCUSSION: A coordinated public health approach is essential to promote healthy aging and mitigate the economic and societal impacts of population aging.

conclusionsThis paper underscores the need for integrated health policies and multidisciplinary care models to ensure that longer life expectancy is accompanied by better quality of life for older individuals.

Indexed as

AgingHealthy AgingLongevityPublic HealthAgedHumansLife ExpectancyQuality of LifeAgingHealthy agingLongevitySenescence

Identifiers

PMID40244306
PMCPMC12006278

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.