Evidence map›Paper›PMID 40244667›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Receptor kinase pathway signal tuning through a nontranscriptional incoherent feedforward loop.

Qian Wang, Yeon Hee Kang, Christian S Hardtke

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Receptor kinase pathway signal tuning through a nontranscriptional incoherent feedforward loop.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Qian WangDepartment of Plant Molecular Biology, University of Lausanne, Lausanne CH-1015, Switzerland.ORCID 0000-0003-1113-1252
Yeon Hee KangDepartment of Plant Molecular Biology, University of Lausanne, Lausanne CH-1015, Switzerland.
Christian S HardtkeDepartment of Plant Molecular Biology, University of Lausanne, Lausanne CH-1015, Switzerland.ORCID 0000-0003-3203-1058

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (SNF) 310030_207876
6 · The paper itself

Abstract

Cellular signaling processes can elicit powerful responses and may need to be amplified to be efficient or dampened to prevent overstimulation. Therefore, they often involve autoregulatory feedbacks. Receptor kinase signaling pathways are abundant in plants, where they convey the presence of both exogenous and endogenous ligands. Among them, endogenous CLAVATA3/EMBRYO SURROUNDING REGION (CLE) peptide signaling acts in an inherently quantitative manner to determine the size of stem cell pools and direct tissue formation. The plant-specific MEMBRANE-ASSOCIATED KINASE REGULATOR (MAKR) family proteins act downstream of receptor kinases. Among the seven family members in

Indexed as

ArabidopsisArabidopsis ProteinsProtein KinasesSignal TransductionCell MembraneFeedback, PhysiologicalGene Expression Regulation, PlantPhosphorylationPhosphotransferasesProtein Serine-Threonine KinasesArabidopsis ProteinsAT2G27250 protein, ArabidopsisAt3g51550 protein, ArabidopsisPhosphotransferasesProtein KinasesProtein Serine-Threonine KinasesArabidopsisCLE peptideMAKRphloemreceptor kinase

Identifiers

PMID40244667
PMCPMC12037008

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.