Evidence map›Paper›PMID 40246786›Full record

ReviewAAPS PharmSciTech2025

Sericin from Bombyx Mori as a By-product for DLP 3D Printing in Pharmaceutical and Biomedical Applications.

Éverton da Silva Santos, Denise Tiemi Uchida, Marcos Luciano Bruschi

Abstract readReview
PubMed Publisher
In one paragraph

Review in AAPS PharmSciTech, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Éverton da Silva SantosLaboratory of Research and Development of Drug Delivery Systems, Postgraduate Program in Pharmaceutical Sciences, Department of Pharmacy, State University of Maringa, Maringa, PR, Brazil.
Denise Tiemi UchidaLaboratory of Research and Development of Drug Delivery Systems, Postgraduate Program in Pharmaceutical Sciences, Department of Pharmacy, State University of Maringa, Maringa, PR, Brazil.
Marcos Luciano BruschiLaboratory of Research and Development of Drug Delivery Systems, Postgraduate Program in Pharmaceutical Sciences, Department of Pharmacy, State University of Maringa, Maringa, PR, Brazil. mlbruschi@uem.br.ORCID http://orcid.org/0000-0002-4838-5742

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sericin, a silk-derived protein, has emerged as a potential material for Digital Light Processing (DLP) printing, particularly in uses requiring biocompatibility and sustainability. Sericin is a candidate for developing durable and precise 3D-printed structures due to its natural origin and intrinsic properties like film-forming ability and cross-linking potential. Its biocompatibility makes it suitable for medical applications, such as targeted delivery of anticancer drugs or creation of therapeutic supports directly on affected skin, orthodontic and cosmetic biomaterials, disease modulation, wound healing, antioxidant and antimicrobial applications, and regenerative medicine. Additionally, sericin can strengthen and stabilize printed structures while maintaining environmental integrity, aligning with the growing demand for eco-friendly materials in advanced manufacturing. However, formulating sericin-based resins for DLP printing presents challenges, including optimizing cross-linking and curing processes for obtaining desired properties of material. Overcoming these challenges could unlock the full potential of sericin in diverse fields, such as tissue engineering, where biocompatibility and precise structural integrity are critical. This review investigates the potential of sericin-based resins for 3D printing, emphasizing the protein's compatibility with photopolymerizable systems and its capacity to improve the overall performance of DLP-printed materials. Further research is essential to refine sericin-based formulations, enabling their broader application in 3D printing technologies. By examining the unique characteristics of sericin, including its origins and material properties, this review underscores the protein's potential to drive innovation in sustainable manufacturing. Ultimately, sericin offers a viable alternative to synthetic resins and holds promise for advancing both biomedical and environmental applications through innovative 3D printing technologies.

Indexed as

BombyxPrinting, Three-DimensionalSericinsAnimalsBiocompatible MaterialsHumansSilkTissue EngineeringBiocompatible MaterialsSericinsSilk3D printingDLPsericinsilktechnology

Identifiers

PMID40246786

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.