ArticleFrontiers in public health2025
Impact of dual sensory impairment on cognition in older Chinese adults: a moderated chain-mediated effect.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Sensory impairment and cognitive impairment among older adults in rural China: personal responsibility for health as a possible moderator?BMC geriatrics · 2026Article
- Sensory impairment and risk of incident depression in older adults: a harmonized longitudinal analysis of 72,177 individuals across six international cohorts.Frontiers in public health · 2026Article
- The relationship between disability, anxiety and depression in older adults with chronic disease comorbidities: the mediating role of frailty.BMC geriatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Although sensory impairment has been identified as a risk factor for cognitive decline, little is known about the underlying mechanisms that connect dual sensory impairment to cognitive ability. This research used a moderated chain-mediated model to investigate the underlying mechanisms behind the association between dual sensory impairment and cognitive ability. Methods: People aged 60 years and older from seven medical institutions, three communities, and five nursing homes in Zunyi city, Guizhou Province, were selected for the study from October 2022 to September 2023 via convenience sampling. Data on demographic characteristics, self-reported hearing and vision loss, and Self-Rating Anxiety Scale (SAS), 15-item Geriatric Depression Scale (GAD-15), Frailty Scale (FRAIL), and Mini-Mental State Examination (MMSE) scores were collected. A moderated chain mediator was used to analyze the underlying mechanisms and pathways of the relationships among anxiety, depression, and cognitive ability in individuals with dual sensory impairment, as well as the moderating role of frailty in this connection. Results: A total of 7,021 older adults were included, 3,598 (51.25%) of whom were male, with a mean age of 72.01 ± 7.17 years. Dual sensory impairment had a significant direct effect on cognitive ability, with an effect size of -3.134, followed by anxiety and depression, which not only independently mediated the relationship between dual sensory impairment and cognitive ability but also jointly had a chain mediation effect, with mediation effect sizes of -0.766 and -0.182, respectively, and a chain mediation effect size of -0.257. In addition, the interaction effect of dual sensory impairment and frailty was significantly predictive of cognitive ability (effect value = -0.575, Conclusion: The mechanisms of action between dual sensory impairment, anxiety, depression, cognitive performance, and frailty are shown in this study. This finding also implies that therapies for psychological issues, frailty, and sensory functioning in older adults can preserve their cognitive ability.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.