Evidence map›Paper›PMID 40248209›Full record

ArticleFrontiers in oncology2025

Improvements in cancer survival in Hungary: a nationwide epidemiology study between 2011-2019 based on a health insurance fund database.

Zoltán Kiss, Anikó Maráz, György Rokszin, Zsolt Horváth, Péter Nagy, Ibolya Fábián, Valéria Kovács, György Surján, Zsófia Barcza, István Kenessey and 23 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Zoltán Kiss *MSD Pharma Hungary Ltd., Budapest, Hungary.
Anikó Maráz *Department of Oncotherapy, University of Szeged, Szeged, Hungary.
György RokszinRxTarget Ltd., Szolnok, Hungary.
Zsolt HorváthDepartment of Oncology, Bács-Kiskun County Teaching Hospital, Kecskemét, Hungary.
Péter NagyDepartment of Molecular Immunology and Toxicology and the National Tumor Biology Laboratory, National Institute of Oncology, Budapest, Hungary.
Ibolya FábiánRxTarget Ltd., Szolnok, Hungary.
Valéria KovácsRxTarget Ltd., Szolnok, Hungary.
György SurjánDepartment of Deputy Chief Medical Officer II., National Public Health Center, Budapest, Hungary.
Zsófia BarczaSyntesia Medical Communications Ltd., Budapest, Hungary.
István KenesseyHungarian National Cancer Registry and National Tumor Biology Laboratory, National Institute of Oncology, Budapest, Hungary.
András WéberHungarian National Cancer Registry and National Tumor Biology Laboratory, National Institute of Oncology, Budapest, Hungary.
István WittmannSecond Department of Medicine and Nephrology-Diabetes Centre, University of Pécs Medical School, Pécs, Hungary.
Gergő Attila MolnárSecond Department of Medicine and Nephrology-Diabetes Centre, University of Pécs Medical School, Pécs, Hungary.
Eszter GyöngyösiMSD Pharma Hungary Ltd., Budapest, Hungary.
Viktória BugaMSD Pharma Hungary Ltd., Budapest, Hungary.
Miklós DaridaMSD Pharma Hungary Ltd., Budapest, Hungary.
Tamás G SzabóMSD Pharma Hungary Ltd., Budapest, Hungary.
Eugenia KaramousouliMSD Pharma Hungary Ltd., Budapest, Hungary.
Zsolt Abonyi-TóthRxTarget Ltd., Szolnok, Hungary.
Renáta Bertókné TamásDepartment of Deputy Chief Medical Officer II., National Public Health Center, Budapest, Hungary.
Diána FürtősDepartment of Deputy Chief Medical Officer II., National Public Health Center, Budapest, Hungary.
Krisztina BogosNational Korányi Institute of Pulmonology, Budapest, Hungary.
Judit Moldvay1st Department of Pulmonology, National Korányi Institute of Pulmonology, Budapest, Hungary.
Gabriella GálffyDepartment of Pulmonology, Pulmonology Center of the Reformed Church in Hungary, Törökbálint, Hungary.
Lilla TamásiDepartment of Pulmonology, Semmelweis University, Budapest, Hungary.
Veronika MüllerDepartment of Pulmonology, Semmelweis University, Budapest, Hungary.
Zoárd Tibor KrasznaiDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Gyula OstorosNational Korányi Institute of Pulmonology, Budapest, Hungary.
Zsolt Pápai-SzékelyFejér County Szent György, University Teaching Hospital, Székesfehérvár, Hungary.
Gabriella Branyiczkiné GéczyDepartment of Population Statistics, Hungarian Central Statistical Office, Budapest, Hungary.
Lászlóné HilbertDepartment of Population Statistics, Hungarian Central Statistical Office, Budapest, Hungary.
Csaba Polgár *National Institute of Oncology and National Tumor Biology Laboratory, Budapest, Hungary.
Zoltán Vokó *Center for Health Technology Assessment, Semmelweis University, Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The assessment of cancer survival is crucial for evaluating advancements in cancer management. As part of the nationwide HUN-CANCER EPI study, we examined the net survival of the Hungarian cancer patient population in 2011-2019. Methods: Using extracted data from the Hungarian National Health Insurance Fund (NHIF) database, the HUN-CANCER EPI study aimed to assess net survival probabilities for various cancer types over the past decade by the Pohar Perme Estimator method, providing insights for sex and age-specific differences and enabling comparative analysis with other European countries. Results: Between 2011 and 2019, 526,381 newly diagnosed cancer cases were identified, with colorectal, lung, breast, prostate, and bladder cancers being the most common. Age-standardized 5-year net survival rates showed significant improvements from 2011-12 till 2017-19 periods for colorectal cancer from 55.08% to 59.78% (4.70%), lung cancer from 20.10% to 23.55% (3.45%), liver cancer from 11.21% to 16.97% (5.76%) and melanoma from 90.06% to 93.80% (3.73%), while clinically relevant, but not significant improvements for breast cancer from 85.03% to 86.84% (1.81%), prostate cancer from 88.13% to 89.76% (1.63%) and thyroid cancer from 87.23% to 92.36% (5.12%). Women generally had better survival probabilities, with notable variations across cancer types. We found no significant age-related differences in cancer survival in women, while survival improvements of colorectal cancer were more pronounced in younger cohorts among male patients. International comparisons using different mortality life tables demonstrated favorable breast and prostate cancer survival rates in Hungary compared to other Central Eastern European countries. Conclusion: The HUN-CANCER EPI study revealed positive trends in cancer survival for most cancer types between 2011 and 2019. The study highlights the continued positive trajectory of cancer survival in Hungary like to more developed European countries.

Indexed as

cancercohort studyHungaryreal world datasurvival

Identifiers

PMID40248209
PMCPMC12004281

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.