Evidence map›Paper›PMID 40249236›Full record

ArticleTissue engineering. Part C, Methods2025

An Abbreviated Rabbit Knee Model of Joint Contracture.

Kareme D Alder, Mason F Carstens, Cole E Bothun, Oliver B Dilger, Ashley N Payne, Roman Thaler, Mark E Morrey, Joaquin Sanchez-Sotelo, Daniel J Berry, Amel Dudakovic and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tissue engineering. Part C, Methods, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kareme D AlderDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Mason F CarstensDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Cole E BothunDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Oliver B DilgerDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Ashley N PayneDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Roman ThalerDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Mark E MorreyDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Joaquin Sanchez-SoteloDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Daniel J BerryDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Amel DudakovicDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Matthew P AbdelDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Funding

Institutional Career Development CoreKL2TR002379 · MAYO CLINIC ROCHESTER · 2025 to 2025
$2.0M
NCATS NIH HHS KL2 TR002379
6 · The paper itself

Abstract

Experimental analyses of knee joint contractures have traditionally utilized a 6-month rabbit model as the gold standard. However, this model is time-intensive and costly. The purpose of this study was to develop an abbreviated rabbit model of knee contractures and compare it to the well-established longer model. Twenty female New Zealand White rabbits were divided into two equal groups and prospectively studied to assess knee passive extension angles (PEA), contracture angles (CA), and terminal posterior capsular stiffness. Experimental knees were immobilized for either 4 weeks (

Indexed as

ContractureDisease Models, AnimalKnee JointAnimalsBiomechanical PhenomenaFemaleRabbitsRange of Motion, Articulararthrofibrosisjoint capsuleknee jointposttraumatic joint contracturerabbit model

Identifiers

PMID40249236
PMCPMC12491957

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.