Evidence map›Paper›PMID 40252010›Full record

ArticlePhysiological reports2025

Exercise frequency affects morphology of aortic calcium deposits in female hyperlipidemic mice as determined by

Nora Safvati, Sophia Kalanski, Andy Hon, Stuti Pradhan, Mimi Lu, Linda L Demer, Yin Tintut

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nora SafvatiDepartment of Medicine, University of California, Los Angeles, California, USA.
Sophia KalanskiDepartment of Medicine, University of California, Los Angeles, California, USA.
Andy HonDepartment of Medicine, University of California, Los Angeles, California, USA.
Stuti PradhanDepartment of Medicine, University of California, Los Angeles, California, USA.
Mimi LuDepartment of Medicine, University of California, Los Angeles, California, USA.
Linda L DemerDepartment of Medicine, University of California, Los Angeles, California, USA.
Yin TintutDepartment of Medicine, University of California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0003-0156-2307

Funding

Role of intermittent activation of parathyroid hormone receptor in exercise-induced vascular calcificationR01HL151391 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DEMER, LINDA L., TINTUT, YIN · 2021 to 2024
$2.2M
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL137647HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL151391NHLBI NIH HHS R01 HL151391
6 · The paper itself

Abstract

While exercise is known to benefit cardiovascular health, the optimum regimen, in terms of both speed and frequency, remains unclear, especially for those with existing calcific atherosclerosis. We previously found that, in atherosclerotic female mice, lower speed, but not higher speed, treadmill running had a beneficial effect on the morphology of aortic calcium mineral deposits, as determined by

Indexed as

AortaAtherosclerosisHyperlipidemiasPhysical Conditioning, AnimalVascular CalcificationAnimalsCalciumFemaleFluorine RadioisotopesMiceMice, Inbred C57BLPositron-Emission TomographySodium FluorideCalciumFluorine-18Fluorine RadioisotopesSodium FluoridecalcificationexercisehyperlipidemiaPET/CT

Identifiers

PMID40252010
PMCPMC12008771

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.