Evidence map›Paper›PMID 40254030›Full record

SynthesisJournal of cachexia, sarcopenia and muscle2025

Effectiveness of Mind-Body Exercise in Older Adults With Sarcopenia and Frailty: A Systematic Review and Meta-Analysis.

Ruihan Wan, Jie Huang, Kangle Wang, Danting Long, Aolong Tao, Jia Huang, Zhizhen Liu

Erratum issuedAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of cachexia, sarcopenia and muscle, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  9. Review
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  11. Frailty in Cancer: Why Bother and Ways Forward.Journal of cachexia, sarcopenia and muscle · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Ruihan WanCollege of Rehabilitation Medicine Fujian University of Traditional Chinese Medicine Fuzhou, Fujian, China.ORCID 0000-0002-8249-8126
Jie HuangCollege of Rehabilitation Medicine Fujian University of Traditional Chinese Medicine Fuzhou, Fujian, China.
Kangle WangCollege of Rehabilitation Medicine Fujian University of Traditional Chinese Medicine Fuzhou, Fujian, China.
Danting LongCollege of Rehabilitation Medicine Fujian University of Traditional Chinese Medicine Fuzhou, Fujian, China.
Aolong TaoCollege of Rehabilitation Medicine Fujian University of Traditional Chinese Medicine Fuzhou, Fujian, China.
Jia HuangCollege of Rehabilitation Medicine Fujian University of Traditional Chinese Medicine Fuzhou, Fujian, China.
Zhizhen LiuNational-Local Joint Engineering Research Center of Rehabilitation Medicine Technology Fujian University of Traditional Chinese Medicine Fuzhou, Fujian, China.ORCID 0000-0001-9645-9120

Funding

Fujian University of Traditional Chinese Medicine Research Fund X2023006Scientific Research Foundation for the Top Youth Talents of Fujian University of Traditional Chinese Medicine XQC2023005Scientific Research Project of Chinese Association of Rehabilitation Medicine KFKT-2022-012The Key Research and Development project funded by the Ministry of Science and Technology of the People's Republic of China 2023YFC3503701
6 · The paper itself

Abstract

backgroundMind-body exercise (MBE) has shown promise in mitigating the effects of sarcopenia and frailty in older adults. Nevertheless, its effectiveness in enhancing muscle function and physical performance in this population has not been well established. This study aimed to investigate the effects of MBE on older adults with sarcopenia and frailty, to offer evidence-based exercise recommendations.

methodsA comprehensive search for randomized controlled trials (RCTs) was conducted through multiple databases, including PubMed, Embase, Cochrane Library, Web of Science, PsycINFO, CINAHL, China National Knowledge Infrastructure (CNKI), WanFang, and Chinese Scientific Journals Full-Text Database (VIP), supplemented by manual reference searches from inception until February 2024. The eligible RCTs compared MBE with passive or active exercise controls, focusing on muscle function and physical performance in older adults aged 60 years or above. Subgroup analyses were conducted to evaluate the types, duration, and frequency of MBE.

resultsNine eligible RCTs with 1838 participants were included in this study. MBE demonstrated significant improvements compared with passive control, particularly in grip strength (WMD [weighted mean difference] = 0.99; 95% CI [95% confidence interval] = 0.06, 1.92; I

conclusionsMBE can enhance muscle function and physical performance to some extent in older adults with sarcopenia and frailty, whether they are compared with passive or active exercise training. However, positive effects on muscle mass have not been observed. Future studies are warranted to compare it with well-designed active exercise training programs that match the exercise volume, to draw more definitive conclusions to support the notion that MBE yields comparable effects.

Indexed as

Exercise TherapyFrailtyMind-Body TherapiesSarcopeniaAgedExerciseHumansMalemeta‐analysismind–body exerciseolder adultssarcopenia and frailty

Identifiers

PMID40254030
PMCPMC12009637

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.