Evidence mapPaperPMID 40255106Full record

ReviewClinical endocrinology2025

Obesity Management in Female Adolescents.

Lauryn P Roth, Angelina Bernier, Lauren Gulley, Kristen Lohse, Rachel Whooten, Leora Allen, Heidi Vanden Brink, Joelle Sfeir, Stacey Simon, Erin Finn and 1 more

Abstract readReview
In one paragraph

Review in Clinical endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lauryn P RothPediatric and Adolescent Gynecology, University of Colorado Anschutz, Aurora, Colorado, USA.
Angelina BernierPediatric Endocrinology, University of Florida Gainsville, Gainsville, Florida, USA.
Lauren GulleyLifestyle Medicine, Children's Hospital Colorado, Aurora, Colorado, USA.
Kristen LohseLifestyle Medicine, Children's Hospital Colorado, Aurora, Colorado, USA.
Rachel WhootenPediatric Endocrinology, Harvard/Mass General, Boston, Massachusetts, USA.
Leora AllenPediatric Endocrinology, Harvard/Mass General, Boston, Massachusetts, USA.
Heidi Vanden BrinkDepartment of Nutrition, Texas A&M University, College Station, Texas, USA.ORCID http://orcid.org/0000-0002-0964-5097
Joelle SfeirDepartment of Nutrition, Texas A&M University, College Station, Texas, USA.
Stacey SimonLudeman Center for Women's Health Research, Aurora, Colorado, USA.
Erin FinnEndocrinology, University of Colorado Anschutz, Aurora, Colorado, USA.
Melanie G CreeLudeman Center for Women's Health Research, Aurora, Colorado, USA.

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · UNIVERSITY OF COLORADO DENVER · 1995 to 2025
$7.7M
Investigating the impact of physical activity in modulating PCOS risk among peripubertal femalesK23DK131322 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · 2024 to 2025
$384k
NIDDK NIH HHS K23 DK107871NIDDK NIH HHS K23 DK131322NIDDK NIH HHS P30 DK048520NIDDK NIH HHS R01 DK120612
6 · The paper itself

Abstract

backgroundGlobal childhood obesity continues to rise, particularly in adolescent females. The underlying cause of this change in prevalence is multifactorial with a complex interplay of genetic, socioeconomic and environmental influences. In this review, we aim to emphasize the multiple options available for assisting an adolescent female to improve their overall health and longevity.

designExperts from each of their respective fields reviewed the current literature regarding the management of obesity in female adolescents.

resultsLifestyle changes, including decreases in overall calorie consumption and simple carbohydrates as well as increases in activity/exercise have been the mainstay of obesity therapy due to their effects on decreasing insulin resistance and associated metabolic disease, as well as weight loss. However, the combination of provider encouraged weight loss and societal obesity stigma leads to an increased risk for disordered eating. The high prevalence of mental health and sleep disorders in female youth with obesity are recent findings, as is the importance in treating these conditions for improved quality of life as well as success with lifestyle changes. The American Academy of Pediatrics' 2023 obesity guidelines are the first across the globe to recommend early adjunctive use of weight loss medications for obesity. These recommendations correspond with the development and increasing availability of new combinations of existing mediations as well as the glucagon like peptide-1 receptor agonist class of medications. Youth with a body mass index in excess of 35-40 kg/m

conclusionThere are now many approaches to consider when treating an adolescent female for obesity or associated metabolic disease, and customized approaches may be needed for optimal success at the individual patient level.

Indexed as

adolescentschildrenfemalemental healthmetabolic diseaseobesityoverweight

Identifiers

PMID40255106
PMCPMC12928152

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.