ArticleFrontiers in public health2025
Machine learning based association between inflammation indicators (NLR, PLR, NPAR, SII, SIRI, and AISI) and all-cause mortality in arthritis patients with hypertension: NHANES 1999-2018.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- CBC-derived inflammatory indices predict adverse outcomes in geriatric emergency patients with acute infectious diarrhea: a MIMIC-IV analysis.Scientific reports · 2026Article
- The neutrophil-percentage-to-albumin ratio (NPAR) shows a nonlinear correlation with all-cause mortality in patients with anemia.Clinical and experimental medicine · 2026Article
- Association of the atherogenic index of plasma and a novel triglyceride-glucose-body shape index with stroke: insights from NHANES and machine learning approaches.BMC cardiovascular disorders · 2026Article
- Positive relationship between an aggregate index of systemic inflammation and stress urinary incontinence: a nationwide cross-sectional analysis.Translational andrology and urology · 2026Article
- Inflammatory marker dynamics in shift work sleep disorder: a data-driven approach among rotating shift workers.Frontiers in neuroscience · 2026Article
- Association Between CBC-Derived Inflammatory Indicators and 28-Day Mortality in Patients With Coronary Heart Disease and Diabetes Mellitus: A Cohort Study From the MIMIC-IV Database.Mediators of inflammation · 2026Article
- Evaluating disease activity scores and CBC-derived indices in relation to osteoporosis risk in rheumatoid arthritis: a cross-sectional analysis.Frontiers in immunology · 2026Article
- Associations between blood cell-based inflammatory indices and their changes and mortality in patients undergoing transcatheter aortic valve replacement: a retrospective investigation with prospective multicenter cohort validation study.International journal of surgery (London, England) · 2025Article
- Composite dietary antioxidant index is inversely associated with all-cause, cardiovascular and cancer mortality in adults with hyperlipidemia.Scientific reports · 2025Article
- Neutrophil-to-albumin ratio: a novel predictor of osteoporosis in rheumatoid arthritis.Frontiers in immunology · 2025Article
Corrections and comments
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Authors and funding
5 authors.
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Abstract
Background: This study aimed to evaluate the relationship between CBC-derived inflammatory markers (NLR, PLR, NPAR, SII, SIRI, and AISI) and all-cause mortality (ACM) risk in arthritis (AR) patients with hypertensive (HTN) using data from the NHANES. Methods: We employed weighted multivariable logistic regression and WQS regression to explore the relationship between inflammatory markers and ACM in AR patients, as well as to determine the weights of different markers. Kaplan-Meier curves, restricted cubic splines (RCS) and ROC curves were utilized to monitor cumulative survival differences, non-linear relationships and diagnostic utility of the markers for ACM risk, respectively. Key markers were selected using XGBoost and LASSO regression machine learning methods, and a nomogram prognostic model was constructed and evaluated through calibration curves and decision curve analysis (DCA). Results: The study included 4,058 AR patients with HTN, with 1,064 deaths over a median 89-month follow-up. All six inflammatory markers were significantly higher in the deceased group ( Conclusion: These results underscore the necessity of monitoring and managing NPAR and SIRI indicators in clinical settings for AR patients with HTN, potentially improving patient survival outcomes.
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