Evidence map›Paper›PMID 40255458›Full record

ArticleComputational and structural biotechnology journal2025

AI-based nanotoxicity data extraction and prediction of nanotoxicity.

Eunyong Ha, Seung Min Ha, Zayakhuu Gerelkhuu, Hyun-Yi Kim, Tae Hyun Yoon

Abstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eunyong HaDepartment of Chemistry, Hanyang University, Seoul 04763, Republic of Korea.
Seung Min HaDepartment of Chemistry, Hanyang University, Seoul 04763, Republic of Korea.
Zayakhuu GerelkhuuResearch Institute for Convergence of Basic Science, Hanyang University, Seoul 04763, Republic of Korea.
Hyun-Yi KimNGeneS Inc., Ansan-si 15495, Republic of Korea.
Tae Hyun YoonDepartment of Chemistry, Hanyang University, Seoul 04763, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the growing use of nanomaterials (NMs), assessing their toxicity has become increasingly important. Among toxicity assessment methods, computational models for predicting nanotoxicity are emerging as alternatives to traditional in vitro and in vivo assays, which involve high costs and ethical concerns. As a result, the qualitative and quantitative importance of data is now widely recognized. However, collecting large, high-quality data is both time-consuming and labor-intensive. Artificial intelligence (AI)-based data extraction techniques hold significant potential for extracting and organizing information from unstructured text. However, the use of large language models (LLMs) and prompt engineering for nanotoxicity data extraction has not been widely studied. In this study, we developed an AI-based automated data extraction pipeline to facilitate efficient data collection. The automation process was implemented using Python-based LangChain. We used 216 nanotoxicity research articles as training data to refine prompts and evaluate LLM performance. Subsequently, the most suitable LLM with refined prompts was used to extract test data, from 605 research articles. As a result, data extraction performance on training data achieved F1

Indexed as

Automated machine learningData extractionLangChainLarge Language ModelsNanotoxicityPrompt engineering

Identifiers

PMID40255458
PMCPMC12008667

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.