Evidence map›Paper›PMID 40255502›Full record

SynthesisFrontiers in endocrinology2025

Obstructive sleep apnea syndrome in polycystic ovary syndrome: a systematic review and meta-analysis.

Nur K Abdul Jafar, Afra Al Balushi, Anuradhaa Subramanian, Siang Ing Lee, Christie J Bennett, Lisa J Moran, Aya Mousa, Chau Thien Tay, Helena J Teede, Darren R Mansfield

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nur K Abdul JafarMonash Centre for Health Research and Implementation, Monash University, Clayton, VIC, Australia.
Afra Al BalushiMonash Lung and Sleep, Monash Health, Clayton, VIC, Australia.
Anuradhaa SubramanianDepartment of Applied Health Sciences, University of Birmingham, Birmingham, United Kingdom.
Siang Ing LeeDepartment of Applied Health Sciences, University of Birmingham, Birmingham, United Kingdom.
Christie J BennettBe Active Sleep and Eat (BASE) Facility, Department of Nutrition, Dietetics and Food, Monash University, Notting Hill, VIC, Australia.
Lisa J MoranMonash Centre for Health Research and Implementation, Monash University, Clayton, VIC, Australia.
Aya MousaMonash Centre for Health Research and Implementation, Monash University, Clayton, VIC, Australia.
Chau Thien TayMonash Centre for Health Research and Implementation, Monash University, Clayton, VIC, Australia.
Helena J TeedeMonash Centre for Health Research and Implementation, Monash University, Clayton, VIC, Australia.
Darren R MansfieldMonash Lung and Sleep, Monash Health, Clayton, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Polycystic ovary syndrome (PCOS) has been associated with a high prevalence of obstructive sleep apnea syndrome (OSAS). However, the impact of OSAS on the PCOS symptom profile remains unclear. This systematic review and meta-analysis, which informed the 2023 International Evidence-based PCOS Guideline, aims to assess the prevalence and related symptoms of OSAS among females with and without PCOS. Methods: A systematic search using databases (MEDLINE, Embase, EBM Reviews, PsycInfo and CINAHL) was performed until 16 Results: From 4438 records, 3205 titles/abstracts were screened and 40 were eligible for full-text screening. Eight cross-sectional studies met inclusion criteria and meta-analysis. The pooled prevalence of OSA was 37.0% in PCOS (29.0% adolescents; 40.0% adults) and 6.0% in non-PCOS. Compared with non-PCOS, those with PCOS showed higher risk for composite OSA (odds ratio (OR): 9.52; 95% CI: 3.90 to 23.26; Conclusion: The prevalence of OSA was higher in PCOS compared with non-PCOS groups, with the risk of OSAS increasing with worse symptom severity. Adults and those of higher BMI and of white ethnicity were at increased risk of OSAS. Hence, identifying and treating OSAS symptoms in PCOS may be beneficial, but further validation of findings is warranted.

Indexed as

Polycystic Ovary SyndromeSleep Apnea, ObstructiveBody Mass IndexFemaleHumansPrevalencemeta-analysisobstructive sleep apnea syndromeOSASpolycystic ovary syndromesystematic review

Identifiers

PMID40255502
PMCPMC12006010

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.