Evidence map›Paper›PMID 40255686›Full record

ArticleReview journal of autism and developmental disorders2025

Language networks in Autism Spectrum Disorder: A systematic review of connectivity-based fMRI studies.

Caroline Larson, Hannah R Thomas, Jason Crutcher, Michael C Stevens, Inge-Marie Eigsti

Abstract read
In one paragraph

Article in Review journal of autism and developmental disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Caroline LarsonDepartment of Psychological Sciences, University of Connecticut, Storrs, CT, USA.
Hannah R ThomasDepartment of Psychological Sciences, University of Connecticut, Storrs, CT, USA.
Jason CrutcherDepartment of Psychological Sciences, University of Connecticut, Storrs, CT, USA.
Michael C StevensOlin Neuropsychiatry Research Center at the Institute of Living, Hartford, CT, USA.
Inge-Marie EigstiDepartment of Psychological Sciences, University of Connecticut, Storrs, CT, USA.

Funding

Optimal Outcomes in ASD: Adult Functioning, Predictors, and MechanismsR01MH112687 · NIMH · UNIVERSITY OF CONNECTICUT STORRS · PI EIGSTI, INGE-MARIE, FEIN, DEBORAH A. · 2018 to 2022
$3.4M
Training in the Cognitive Neuroscience of CommunicationT32DC017703 · NIDCD · UNIVERSITY OF CONNECTICUT STORRS · PI Inge-Marie Eigsti, Emily B Myers · 2019 to 2026
$2.3M
NIDCD NIH HHS T32 DC017703NIMH NIH HHS R01 MH112687
6 · The paper itself

Abstract

Autism Spectrum Disorder (ASD) is a heterogeneous condition associated with differences in functional neural connectivity relative to neurotypical (NT) peers. Language-based functional connectivity represents an ideal context in which to characterize connectivity because language is heterogeneous and linked to core features in ASD, and NT language networks are well-defined. We conducted a systematic review of language-related functional connectivity literature on individuals with ASD using PubMed, PsychInfo, Scopus, ProQuest, and Google Scholar, yielding 96 studies. Language-task studies indicated local over-connectivity within the language network and global under-connectivity of language with out-of-network regions in ASD. Resting-state studies showed mixed patterns, and connectivity was associated ASD symptomology and language skills. This evidence indicates language-task elicited local over-connectivity and global under-connectivity in ASD, but not a local versus global distinction of resting-state language-related connectivity. Associations with behavior suggest that local over-connectivity and global under-connectivity characterize ASD, and heightened language-related connectivity may support social function.

Indexed as

Autism Spectrum DisorderFunctional ConnectivityFunctional Magnetic Resonance ImagingLanguage

Identifiers

PMID40255686
PMCPMC12007812

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.