Evidence map›Paper›PMID 40255688›Full record

ArticleFrontiers in dental medicine2025

Antibiofilm potential of plant extracts: inhibiting oral microorganisms and

Nomi Bartels, Aikaterini Argyropoulou, Ali Al-Ahmad, Elmar Hellwig, Alexios Leandros Skaltsounis, Annette Wittmer, Kirstin Vach, Lamprini Karygianni

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in dental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Current Knowledge of the GenusPharmaceuticals (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nomi BartelsDepartment of Prosthodontics, Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany.
Aikaterini ArgyropoulouDepartment of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece.
Ali Al-AhmadDepartment of Operative Dentistry and Periodontology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Elmar HellwigDepartment of Operative Dentistry and Periodontology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Alexios Leandros SkaltsounisDepartment of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Athens, Greece.
Annette WittmerInstitute of Medical Microbiology and Hygiene, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Kirstin VachInstitute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Lamprini KarygianniClinic of Conservative and Preventive Dentistry, Center of Dental Medicine University of Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: A range of disinfectant mouthwashes are available for oral hygiene. The gold standard is Chlorhexidine digluconate (CHX), which, like other available products, cannot be used without side effects in the long term. However, in recent years, therapy with herbal products, often considered antiquated, has regained considerable interest. Therefore, the search for plant compounds as an alternative to existing oral disinfectants is meaningful. Methods: In this study, eleven Mediterranean plant extracts were tested for their antimicrobial effect Results: All extracts, except the methanol extract of Discussion: The study's hypothesis that all extracts would exhibit an antimicrobial effect was thus confirmed.

Indexed as

antimicrobial activitybiofilm inhibitionMediterranean herb extractsoral mouthwashesStreptococcus mutans

Identifiers

PMID40255688
PMCPMC12006170

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.