Evidence map›Paper›PMID 40256111›Full record

ArticleJournal of multidisciplinary healthcare2025

Bibliometric and Visual Analysis of Alzheimer's Disease and Herpes Simplex Virus Type 1 Infection Between 1990 and 2024.

Hongling Ren, Ruiyao Song, Hairong Wang, Qingyan Zeng, Yu Fu, Yunchu Guo, Ying Xie, Yusong Ge

Abstract read
In one paragraph

Article in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hongling RenThe Department of Neurology, the second Affiliated Hospital of Dalian Medical University, Dalian City, Liaoning Province, 116023, People's Republic of China.
Ruiyao SongThe Department of Neurology, the second Affiliated Hospital of Dalian Medical University, Dalian City, Liaoning Province, 116023, People's Republic of China.
Hairong WangThe Department of Neurology, the second Affiliated Hospital of Dalian Medical University, Dalian City, Liaoning Province, 116023, People's Republic of China.
Qingyan ZengThe Department of Neurology, the second Affiliated Hospital of Dalian Medical University, Dalian City, Liaoning Province, 116023, People's Republic of China.
Yu FuThe Department of Neurology, the second Affiliated Hospital of Dalian Medical University, Dalian City, Liaoning Province, 116023, People's Republic of China.
Yunchu GuoThe Department of Neurology, the second Affiliated Hospital of Dalian Medical University, Dalian City, Liaoning Province, 116023, People's Republic of China.
Ying XieThe Department of Infection Control and Prevention, the second Affiliated Hospital of Dalian Medical University, Dalian City, Liaoning Province, 116023, People's Republic of China.
Yusong GeThe Department of Neurology, the second Affiliated Hospital of Dalian Medical University, Dalian City, Liaoning Province, 116023, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recently, some studies suggested that Herpes simplex virus type 1 (HSV-1) infection is an important environmental factor for Alzheimer's disease(AD). The literature on research about HSV-1 infection and AD is emerging. This study used the bibliometric method to investigate the relationship between HSV-1 infection and AD. Methods: We searched the Web of Science Core Collection for relevant literature on AD and HSV-1 from 1990 to 2024. Bibliometric and visualization analyses were performed using VOSviewer and CiteSpace. Results: From 1990 to 2024, the number of publications showed an increasing trend. The United States made the largest contributions in productivity. The University of Manchester was the most productive organization. Professor Ruth F. Itzhaki was the most influential researcher. The Journal of Alzheimer's Disease had published the most articles. Research on the mechanisms by which HSV infection contributes to AD remains a hotspot in the field, and future studies may further focus on antiviral therapeutic strategies targeting HSV-1 infection. Conclusion: Our analysis provides basic information about research in AD and HSV-1. The current research hotspots in this field mainly include the mechanism of AD caused by HSV-1, and antiviral drugs to treat or prevent AD.

Indexed as

Alzheimer’s diseasebibliometriccitespaceHerpes simplex virus type 1visualized analysisVOSviewer

Identifiers

PMID40256111
PMCPMC12009126

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.