Evidence map›Paper›PMID 40256142›Full record

ReviewHealth science reports2025

Adherence to Mediterranean Diet and Breast Cancer Risk: A Meta-Analysis of Prospective Observational Studies.

Mehdi Karimi, Omid Asbaghi, Farnaz Hooshmand, Amir Hossein Aghayan, Amir Ahmad Shariati, Kimia Kazemi, Mahdi Amirpour, Sayed Hosein Davoodi, Bagher Larijani

Abstract readReview
In one paragraph

Review in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mehdi KarimiFaculty of Medicine Bogomolets National Medical University (NMU) Kyiv Ukraine.ORCID 0009-0006-4388-0214
Omid AsbaghiCancer Research Center Shahid Beheshti University of Medical Sciences (SBUMS) Tehran Iran.ORCID 0000-0002-7740-4711
Farnaz HooshmandFaculty of Medicine Golestan University of Medical Science Gorgan Iran.ORCID 0000-0003-4048-6626
Amir Hossein AghayanDepartment of Medical Laboratory Sciences, School of Allied Medical Sciences Shahroud University of Medical Sciences Shahroud Iran.ORCID 0000-0002-6843-9664
Amir Ahmad ShariatiDepartment of Nutrition Sciences, School of Health Arak University of Medical Sciences Arak Iran.ORCID 0009-0007-2723-8720
Kimia KazemiDepartment of Food Science and Technology Islamic Azad University, Ayatollah Amoli Branch Amol Iran.
Mahdi AmirpourDepartment of Clinical Nutrition & Dietetics Shahid Beheshti University of Medical Sciences (SBUMS) Tehran Iran.
Sayed Hosein DavoodiNational Nutrition and Food Technology Research Institute Shahid Beheshti University of Medical Sciences (SBUMS) Tehran Iran.ORCID 0000-0002-6404-8367
Bagher LarijaniEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute Tehran University of Medical Sciences Tehran Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: The Mediterranean diet (MD) is widely recognized for its health benefits and potential protective effects against various chronic diseases such as cardiovascular conditions and cancer. This meta-analysis evaluates the association between MD adherence and breast cancer risk in women. Methods: A comprehensive search of major databases was conducted until November 2024 to identify cohort or case-control studies. The meta-analysis employed a random-effects model to pool multivariable-adjusted effect sizes, reporting them as hazard ratios (HR) while evaluating heterogeneity using the I² statistic and assessing publication bias. Results: The pooled analysis of 31 studies indicated a significant association between adherence to the MD and a 13% risk reduction in risk of breast cancer (HR: 0.87, 95% CI: 0.82-0.92; Conclusion: Adherence to the Mediterranean diet is associated with a significant reduction in breast cancer risk, particularly among postmenopausal women and in regions such as Asia. These findings suggest that the Mediterranean diet may be an important dietary factor in reducing breast cancer risk, especially in certain populations. However, further research is needed to confirm its impact in different study designs and geographical areas.

Indexed as

cancer riskclinical nutritiondietary patternepidemiologyMediterranean dietoncology

Identifiers

PMID40256142
PMCPMC12007187

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.