Evidence map›Paper›PMID 40256245›Full record

ArticleJournal of diabetes research2025

Umbilical Cord Mesenchymal Stem Cells Attenuate Podocyte Injury in Diabetic Nephropathy Rats by Inhibiting Angpltl4/Integrin

Shiyuan Liu, Mingyao Meng, Chunkai Huang, Lijia He, Pu Wang, Zhe Tang, Xi Ran, Hui Gao, Yangfan Guo, Yan He and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Shiyuan LiuYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.
Mingyao MengYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.ORCID https://orcid.org/0000-0002-9766-414X
Chunkai HuangYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.
Lijia HeYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.
Pu WangYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.
Zhe TangYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.
Xi RanYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.
Hui GaoYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.
Yangfan GuoYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.
Yan HeYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.
Jian ChenYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.
Haiyan HuYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.
Shan HeYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.
Yiyi ZhaoYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.
Zongliu HouYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.ORCID https://orcid.org/0000-0003-3536-7550
Lin LiYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.ORCID https://orcid.org/0000-0002-2886-2839
Wenhong LiYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.
Wenju WangYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.ORCID https://orcid.org/0000-0002-8066-1380
Xiaodan WangYan'an Hospital Affiliated to Kunming Medical University, Kunming, China.ORCID https://orcid.org/0000-0002-2680-6825

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we investigated the therapeutic effects and mechanisms of umbilical cord mesenchymal stem cells (UCMSCs) in diabetic nephropathy (DN) ZDF (FA/FA) rats. The therapeutic effects were assessed by renal function tests, the urinary albumin-creatinine ratio, PAS staining, electron microscopy, and TGF-

Indexed as

Angiopoietin-Like Protein 4Diabetic NephropathiesIntegrin beta3Kidney GlomerulusMesenchymal Stem CellsMesenchymal Stem Cell TransplantationPodocytesUmbilical CordAnimalsFibronectinsIntracellular Signaling Peptides and ProteinsMaleMembrane ProteinsMicrofilament ProteinsRatsTransforming Growth Factor beta1Angiopoietin-Like Protein 4ANGPTL4 protein, ratFibronectinsIntegrin beta3Intracellular Signaling Peptides and ProteinsMembrane ProteinsMicrofilament ProteinsNPHS2 proteinSynpo protein, ratTransforming Growth Factor beta1

Identifiers

PMID40256245
PMCPMC12008490

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.