Evidence map›Paper›PMID 40258053›Full record

ArticleCirculation2025

Integrin Targeting Therapies in Pulmonary Arterial Hypertension: A Roadmap for Traversing the Translational Valley of Death?

Vineet Agrawal, Anna R Hemnes

Abstract readEditorialComment
In one paragraph

Article in Circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Vineet AgrawalPulmonary Circulation Center (V.A., A.R.H.), Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0002-8457-6722
Anna R HemnesPulmonary Circulation Center (V.A., A.R.H.), Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0002-2755-5845

Funding

Genomic and Circulating Predictors of PAH responseR01HL142720 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Anna R Hemnes · 2019 to 2026
$5.0M
Network Medicine and Systems Pharmacology to Advance Precision Medicine in Combined Pulmonary HypertensionR01HL163960 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Evan L Brittain, Anna R Hemnes · 2022 to 2026
$3.4M
Mentorship in Pulmonary Vascular DiseaseK24HL155891 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Anna R Hemnes · 2022 to 2026
$573k
BLRD VA IK2 BX005828FDA HHS R01 FD007627NHLBI NIH HHS K24 HL155891NHLBI NIH HHS R01 HL142720NHLBI NIH HHS R01 HL163960
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Editorialsfamilial primary pulmonary hypertensionpulmonary arterial hypertension

Identifiers

PMID40258053
PMCPMC12014143

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.