ArticleBMC cardiovascular disorders2025
Diagnostic value of transesophageal echocardiography on morphology and function of left atrial appendage in patients with unclosed foramen ovale complicated with atrial fibrillation.
Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study investigates the diagnostic value of transesophageal echocardiography (TEE) for assessing the left atrial appendage (LAA) in patients with patent foramen ovale (PFO) and atrial fibrillation (AF). TEE provides detailed images that help evaluate the morphology and function of the LAA, which are crucial in diagnosing and managing these conditions.
methodsThe study included 104 PFO patients admitted between December 2021 and January 2024, divided into AF (n = 53) and non-AF groups (n = 51). Additionally, 30 healthy individuals served as controls. All participants underwent TEE to compare ultrasound indices, LAA morphology, and function. The diagnostic values of these measurements were analyzed and compared across the three groups.
resultsThe AF group had a larger left atrial diameter (LAD) compared to the non-AF and control groups (P < 0.001). Both PFO groups had lower left ventricular ejection fractions (LVEF) than controls (P < 0.001), with the AF group showing lower LVEF than the non-AF group (P < 0.001). The AF group's LAA long diameter was greater (P < 0.05). LAA ejection fraction (LAAEF) and maximal emptying velocity (LAAPEV) were lower in PFO groups compared to controls, with the AF group also lower than the non-AF group (P < 0.01). Combined diagnostic measurements of LAA parameters showed higher accuracy (AUC = 0.979) than single measurements.
conclusionsTEE evaluates LAA morphology and function effectively, providing significant diagnostic value for PFO with AF. Combined diagnostic parameters yield high specificity and sensitivity, enhancing diagnostic accuracy.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.