Evidence map›Paper›PMID 40259728›Full record

ArticleObesity (Silver Spring, Md.)2025

Functional mobility and pain are improved for 6 years after adolescent bariatric surgery.

Neil Thivalapill, Todd M Jenkins, Thomas H Inge, Changchun Xie, Anita P Courcoulas, Carroll M Harmon, Michael A Helmrath, Stephanie Sisley, Marc P Michalsky, Justin R Ryder and 1 more

Abstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Neil ThivalapillDepartment of Surgery, Weill Cornell Medicine, New York, New York, USA.ORCID https://orcid.org/0000-0003-3398-6710
Todd M JenkinsUniversity of Cincinnati, College of Medicine, Cincinnati, Ohio, USA.
Thomas H IngeDepartment of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0001-7782-1112
Changchun XieUniversity of Cincinnati, College of Medicine, Cincinnati, Ohio, USA.
Anita P CourcoulasDepartment of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Carroll M HarmonJohn R. Oishei Children's Hospital and Jacobs School of Medicine and Biomedical Sciences, State University of New York University at Buffalo, Buffalo, New York, USA.
Michael A HelmrathDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Stephanie SisleyUS Department of Agriculture/Agricultural Research Service Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
Marc P MichalskyDepartment of Pediatric Surgery, Nationwide Children's Hospital and The Ohio State University College of Medicine Columbus, Columbus, Ohio, USA.
Justin R RyderDepartment of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Teen‐Longitudinal Assessment of Bariatric Surgery (Teen‐LABS) consortium

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Research ProjectUM1DK072493 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI INGE, THOMAS HARRIS · 2011 to 2020
$10.5M
Cincinnati Center for Clinical and Translational Sciences and TrainingUL1TR000077 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., TSEVAT, JOEL · 2012 to 2014
$9.9M
Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) renewalUM1DK095710 · NIDDK · UNIVERSITY OF CINCINNATI · PI JENKINS, TODD M, XIE, CHANGCHUN · 2011 to 2020
$9.4M
Adolescent Bariatrics: Assessing Health Benefits & RisksU01DK072493 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI INGE, THOMAS HARRIS · 2006 to 2010
$8.7M
National Center for Research Resources and the National Center for Advancing Translational Sciences, NIH 8UL1TR000077National Center for Research Resources and the National Center for Advancing Translational Sciences, NIH UL1TR000114NCATS NIH HHS UL1 TR000077NCATS NIH HHS UL1 TR000114NIDDK NIH HHS U01 DK072493NIDDK NIH HHS UM1 DK072493NIDDK NIH HHS UM1 DK095710NIH HHS U01DK072493NIH HHS UM1DK072493NIH HHS UM1DK095710
6 · The paper itself

Abstract

objectiveThe long-term durability of improvements in functional mobility and musculoskeletal pain for adolescents after metabolic and bariatric surgery (MBS) is unknown.

methodsWe used the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study to determine the change in mobility and pain among adolescents who underwent MBS. From standardized 400-m walk tests, we analyzed walk time, heart rate (HR) parameters, and musculoskeletal pain.

resultsThe mean walk time improved from 383 s (95% CI: 368-399) prior to surgery to 351 s (95% CI: 330-372) by 6 years. The mean resting HR was 90 beats per minute (bpm; 95% CI: 87-93) preoperatively and decreased to 80 bpm (95% CI: 76-84) by 6 years. The risk of any musculoskeletal pain decreased from 37.2% (95% CI: 25.5%-48.9%) to 11.0% (95% CI: 4.3%-17.6%) by 6 years. Mediation analysis revealed that the effect of time since surgery on walk time, resting HR, and HR recovery occurred through a weight-dependent mechanism. For posttest HR and HR difference, there was both a significant weight-dependent and weight-independent mechanism. The effect of surgery on the risk of musculoskeletal pain occurred through a weight-independent mechanism.

conclusionsAdolescents who underwent MBS experienced significant, durable improvement in mobility and pain, despite weight regain. Our models suggest that improvements may occur through a weight-independent mechanism.

Indexed as

Bariatric SurgeryMusculoskeletal PainPediatric ObesityAdolescentFemaleHeart RateHumansLongitudinal StudiesMaleTreatment OutcomeWalking

Identifiers

PMID40259728
PMCPMC12119214

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.