ArticleBMC public health2025
The association between social determinants of health and all-cause, cardiovascular mortality in US rheumatoid arthritis: a cohort study of NHANES.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Article
- Letter to the editor: social determinants of health in managing late-onset rheumatoid arthritis.Rheumatology international · 2025Article
- Social determinants of health and all-cause or cardiovascular mortality on osteoarthritis adults in the USA: a national cohort study.Frontiers in public health · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRheumatoid arthritis (RA) imposes a significant burden on healthcare systems. This study investigates the impact of social determinants of health (SDoH) on the prognosis of RA patients, aiming to inform interventions that improve health outcomes.
methodsThe National Health and Nutrition Examination Survey (NHANES) 2005-2018 included 2,024 RA participants. SDoH was assessed based on the five domains outlined in the Healthy People 2030 framework, with the cumulative number of adverse SDoH calculated. Cox regression analysis, subgroup analysis, and Kaplan-Meier survival analysis were employed to evaluate the associations between SDoH and all-cause mortality as well as cardiovascular mortality among RA patients, adjusting for potential confounding factors.
resultsOver a median follow-up of 79 months, 449 deaths (19%) occurred, including 120 cardiovascular deaths. Each 1-point increase in cumulative SDoH score was linked to a 24% higher risk of all-cause mortality (HR: 1.24; 95% CI: 1.16-1.32; p < 0.001) and a 25% higher risk of cardiovascular mortality (HR: 1.25; 95% CI: 1.13-1.39; p < 0.001). Exposure to five or more adverse SDoH was associated with a higher risk of all-cause mortality (HR: 3.94; 95% CI: 2.20-7.06; p < 0.001) as well as cardiovascular mortality (HR: 3.98; 95% CI: 1.22-12.97; p = 0.020). Significant interactions were found between SDoH and age, income, and education level.
conclusionAdverse SDoH, particularly when accumulated, are associated with increased mortality risks in RA patients, emphasizing the need for targeted interventions to mitigate these effects.
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