Evidence map›Paper›PMID 40266938›Full record

ArticleVeterinary sciences2025

Antioxidant Activity, Phenolic Acid, and Flavonoid Composition of an Antiseptic Ointment Based on Aloe and Green Propolis and Its Potential for Preventing Mastitis in Dairy Cows.

Sílvia Cristina de Aguiar, Solange Maria Cottica, Silvério Teixeira Dos Santos, Juliana Maxiano da Fonseca, Luiza da Silva Leite, Mylena Leite da Silva

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Antimicrobial activity of brown propolis ethanolic extract and its application in intramammary formulation for the treatment of bovine mastitis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sílvia Cristina de AguiarDepartment of Animal Science, Universidade do Estado de Mato Grosso-UNEMAT, Pontes e Lacerda 78250000, Brazil.ORCID 0000-0001-5497-2559
Solange Maria CotticaPrograma de Pós-Graduação em Processos Químicos e Biotecnológicos, Universidade Tecnológica Federal do Paraná, Toledo 85902490, Brazil.ORCID 0000-0003-3183-2531
Silvério Teixeira Dos SantosDepartment of Animal Science, Universidade do Estado de Mato Grosso-UNEMAT, Pontes e Lacerda 78250000, Brazil.
Juliana Maxiano da FonsecaDepartment of Animal Science, Universidade do Estado de Mato Grosso-UNEMAT, Pontes e Lacerda 78250000, Brazil.
Luiza da Silva LeiteBioprocess Engineering and Biotechnology, Universidade Tecnológica Federal do Paraná, Toledo 85902490, Brazil.
Mylena Leite da SilvaDepartment of Animal Science, Universidade do Estado de Mato Grosso-UNEMAT, Pontes e Lacerda 78250000, Brazil.

Funding

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE MATO GROSSO - FAPEMAT 0000083/2022.
6 · The paper itself

Abstract

Mastitis is a major challenge in dairy production, leading to decreased milk yield and quality due to increased somatic cell counts (SCCs). The overuse of antibiotics to treat this condition has raised concerns about antimicrobial resistance, prompting the search for alternative treatments. This study aimed to evaluate the antioxidant activity, phenolic acid, and flavonoid content of a natural antiseptic ointment based on green propolis and aloe vera. The phenolic and flavonoid composition was determined using ultra-high-performance liquid chromatography, revealing high concentrations of bioactive compounds, particularly in the green propolis extract. The antioxidant activity was assessed using the DPPH method, and the ointment was applied as a post-dipping treatment in dairy cows. Over a 56-day period, the SCC in cows treated with the ointment showed a significant reduction (

Indexed as

antimicrobial activityBaccharis dracunculifoliamastitis preventionmilkphenolic compoundssomatic cell count

Identifiers

PMID40266938
PMCPMC11945798

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.