Evidence map›Paper›PMID 40266979›Full record

ReviewVeterinary sciences2025

West Nile Virus (WNV): One-Health and Eco-Health Global Risks.

Luigi Bruno, Maria Anna Nappo, Raffaele Frontoso, Maria Gabriella Perrotta, Rosanna Di Lecce, Chiara Guarnieri, Luca Ferrari, Attilio Corradi

Abstract readReview
In one paragraph

Review in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Cellular Immune Response in Horses After West Nile Neuroinvasive Disease.Animals : an open access journal from MDPI · 2025
    Article
  17. Review
  18. West Nile virus unmasked: from gene variability to future challenges.Frontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luigi BrunoDepartment of Prevention, Azienda Sanitaria Locale (A.S.L.) Napoli 3 Sud, Castellammare di Stabia, 80053 Naples, Italy.
Maria Anna NappoDepartment of Prevention, Azienda Sanitaria Locale (A.S.L.) Napoli 3 Sud, Castellammare di Stabia, 80053 Naples, Italy.
Raffaele FrontosoIstituto Zooprofilattico Sperimentale del Mezzogiorno (I.Z.S.M.), Portici, 80055 Naples, Italy.ORCID 0009-0008-9421-796X
Maria Gabriella PerrottaMinistry of Health, Office 3 exDGSAF of the General Directorate of Animal Health, 00144 Rome, Italy.
Rosanna Di LecceDepartment of Veterinary Science, University of Parma, 43126 Parma, Italy.
Chiara GuarnieriDepartment of Veterinary Science, University of Parma, 43126 Parma, Italy.ORCID 0000-0002-7033-0596
Luca FerrariDepartment of Veterinary Science, University of Parma, 43126 Parma, Italy.ORCID 0000-0002-5428-1595
Attilio CorradiDepartment of Veterinary Science, University of Parma, 43126 Parma, Italy.ORCID 0000-0002-4511-9748

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

West Nile virus (WNV) is an important zoonotic pathogen belonging to the Flaviviridae family, which is endemic in some areas and emerging in others. WNV is transmitted by blood-sucking mosquitoes of the genus Culicoides, Aedes, and Anopheles, and the infection can cause different clinical symptoms. The most common and benign illness in humans is West Nile fever (WNF), but a lethal neurological disease (WNND), related to the neuro-invasiveness of WNV lineage 2, represents the highest health risk of WNV infection. The neuro-clinical form is recognized in mammals (land and cetaceans), particularly in humans (elderly or immunosuppressed) and in horses, avian species, and wildlife animals ranging free or in a zoological setting. This review highlights the most relevant data regarding epidemiology, virology, pathogenesis and immunity, clinical signs and differential diagnosis, pathology and imaging, histopathology and gross pathology, economic impact, influence of climate change, and surveillance of WNV. Climate change has favored the wide spread of WNV in many areas of the globe and consequent One-Health and Eco-Health emergencies, influencing the health of human beings, animals, and ecosystems.

Indexed as

clinical signsdiagnosiseco-healtheconomic impactepidemiologyimmune responselegislationone-healthpathogenesispathologysurveillanceWest Nile virus (WNV)

Identifiers

PMID40266979
PMCPMC11945822

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.