Evidence map›Paper›PMID 40267446›Full record

ArticleStroke2025

Association Between Real-World Actigraphy and Poststroke Motor Recovery.

Keith R Lohse, Allison E Miller, Marghuretta D Bland, Jin-Moo Lee, Catherine E Lang

Abstract readMulticenter Study
In one paragraph

Article in Stroke, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Keith R LohseProgram in Physical Therapy (K.R.L., A.E.M., M.D.B., C.E.L.), Washington University School of Medicine, St Louis, MO.ORCID 0000-0002-7643-3887
Allison E MillerProgram in Physical Therapy (K.R.L., A.E.M., M.D.B., C.E.L.), Washington University School of Medicine, St Louis, MO.ORCID 0000-0003-3043-6852
Marghuretta D BlandProgram in Physical Therapy (K.R.L., A.E.M., M.D.B., C.E.L.), Washington University School of Medicine, St Louis, MO.ORCID 0000-0001-9091-2764
Jin-Moo LeeDepartment of Neurology (K.R.L., M.D.B., J.-M.L., C.E.L.), Washington University School of Medicine, St Louis, MO.ORCID 0000-0002-3979-0906
Catherine E LangProgram in Physical Therapy (K.R.L., A.E.M., M.D.B., C.E.L.), Washington University School of Medicine, St Louis, MO.ORCID 0000-0002-7120-0136

Funding

DOCTORAL TRAINING PROGRAM IN MOVEMENT SCIENCET32HD007434 · NICHD · WASHINGTON UNIVERSITY · PI Michael D Harris, Catherine Lang · 1993 to 2026
$4.2M
Plasticizing the Cortex to Enhance Stroke RecoveryR37NS110699 · NINDS · WASHINGTON UNIVERSITY · PI LEE, JIN-MOO · 2019 to 2025
$3.5M
Genetic Architecture of Acute Human Brain IschemiaR01NS085419 · NINDS · WASHINGTON UNIVERSITY · PI CRUCHAGA, CARLOS, LEE, JIN-MOO · 2014 to 2018
$2.8M
Translation of In-Clinic Gains to Gains in Daily LifeR37HD068290 · NICHD · WASHINGTON UNIVERSITY · PI Catherine Lang · 2022 to 2026
$2.7M
Building a data science workforce to improve the reproducibility of rehabilitation researchR25HD105583 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI David Nelson Kennedy, Sook-Lei Liew · 2022 to 2026
$812k
NICHD NIH HHS R25 HD105583NICHD NIH HHS R37 HD068290NICHD NIH HHS T32 HD007434NINDS NIH HHS R01 NS085419NINDS NIH HHS R37 NS110699
6 · The paper itself

Abstract

backgroundStroke is a leading cause of long-term disability, but advances for rehabilitation have lagged those for acute treatment. Large biological studies (eg, omics) may offer mechanistic insights for recovery but require collecting detailed recovery phenotypes at scale, for example, in thousands of people with minimal burden for participants and researchers. This study investigates the concurrent validity between remotely collected wearable sensor data and in-clinic assessments of motor recovery poststroke.

methodsUtilizing a large, harmonized multisite dataset of adults at various stages of recovery poststroke, we analyzed cross-sectional (N=198; from 0 to >52 weeks) and longitudinal (N=98; from 0 to 26 weeks) changes in the use ratio, the Action Research Arm Test, and the Fugl-Meyer Assessment upper extremity subscale. The use ratio is the ratio of the time the paretic arm is active divided by the time the nonparetic arm is active.

resultsOur findings indicate strong concurrent validity of the use ratio, the Action Research Arm Test, and the Fugl-Meyer Assessment upper extremity subscale both cross-sectionally (differences between people) and longitudinally (changes within a person), for example,

conclusionsAlthough the use ratio strongly correlated with the Fugl-Meyer Assessment upper extremity subscale and Action Research Arm Test early after stroke, these correlations reduced with longer elapsed time poststroke. This decreasing correlation might be explained by the increasing influence that personal and environmental factors play as recovery progresses.

Indexed as

ActigraphyRecovery of FunctionStrokeStroke RehabilitationAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedUpper Extremityactigraphyarmremote patient monitoringstrokeupper extremity

Identifiers

PMID40267446
PMCPMC12303754

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.