Evidence map›Paper›PMID 40268337›Full record

ArticleStroke and vascular neurology2025

Peripheral blood

Yohei Mineharu, Takahiko Kamata, Mei Tomoto, Noriaki Sato, Yoshinori Tamada, Takeshi Funaki, Yuki Oichi, Kouji H Harada, Akio Koizumi, Tetsuaki Kimura and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stroke and vascular neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yohei MineharuDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan mineharu@kuhp.kyoto-u.ac.jp.ORCID 0000-0002-6346-3999
Takahiko KamataDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Mei TomotoDepartment of Biomedical Data Intelligence, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Noriaki SatoDepartment of Biomedical Data Intelligence, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0001-7721-9359
Yoshinori TamadaInnovation Center for Health Promotion, Hirosaki University, Hirosaki, Japan.ORCID 0000-0003-3483-9712
Takeshi FunakiDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0001-9489-7469
Yuki OichiDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0002-0225-8158
Kouji H HaradaDepartment of Health and Environmental Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0001-7319-123X
Akio KoizumiSocial Health Medicine Welfare Laboratory, Public Interest Incorporated Association Kyoto Hokenkai, Kyoto, Japan.
Tetsuaki KimuraDivision of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Mishima, Japan.
Ituro InoueDivision of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Mishima, Japan.
Yasushi OkunoDepartment of Artificial Intelligence in Healthcare and Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Susumu MiyamotoMoyamoya Disease Support Center, Stroke Support Center, Kyoto University Hospital, Kyoto, Japan.ORCID 0000-0002-3648-3572
Yoshiki ArakawaDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0003-4626-4645

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe p.R4810K founder mutation in the METHODS AND

resultsTranscriptome analysis of peripheral blood was conducted with nine MMD patients and five unaffected mutation carriers from four familial MMD pedigrees. Bayesian network analysis identified upregulated gene modules associated with lipid metabolism and leucocyte development (including

conclusionsPeripheral blood

Indexed as

Adenosine TriphosphatasesGATA2 Transcription FactorMoyamoya DiseaseMutationPenetranceUbiquitin-Protein LigasesAdolescentAdultCase-Control StudiesChildFemaleGene Expression ProfilingGene Regulatory NetworksGenetic Association StudiesGenetic Predisposition to DiseaseHeterozygoteAdenosine TriphosphatasesGATA2 protein, humanGATA2 Transcription FactorRNF213 protein, humanUbiquitin-Protein LigasesCerebrovascular DisordersGeneticsRisk FactorsStroke

Identifiers

PMID40268337
PMCPMC12772967

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.