ArticleScientific reports2025
Hematological reference intervals for adult population of Debre Berhan town, North East Ethiopia.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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10 authors.
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Abstract
Accurate hematological reference intervals are critical for proper disease diagnosis and patient management. However, many Ethiopian laboratories rely on reference intervals derived from Western populations, which may not reflect the genetic, environmental, and lifestyle factors of the local population. This study aimed to establish locally derived hematological reference intervals for adults in Debre Berhan town, North East Ethiopia. A community-based cross-sectional study was conducted in Debre Berhan town Northeast Ethiopia, from May to July 2024. Two hundred forty (120 male, 120 female) apparently healthy adults were recruited using convenient sampling. Sociodemographic data were collected via Interviewer-administered pre-tested questionnaire through KoBoToolbox. Aseptically collected venous blood samples were analyzed for hematological parameters using a Mindray 5150 analyzer. Data were analyzed using Stata version 17; the 2.5th and 97.5th percentiles were used to determine RIs, and the Mann-Whitney U test was used to assess gender-based differences, with statistical significance set at p < 0.05. The established 95% hematological reference intervals (2.5th-97.5th percentile) were: WBC (3.2-9.5 × 10
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