Evidence map›Paper›PMID 40270321›Full record

ArticleACS applied bio materials2025

Antifouling Activity of Bottlebrush Network Hydrogels.

Meng-Chen Chiang, Brandon R Clarke, Gregory N Tew, Jessica D Schiffman

Abstract read
In one paragraph

Article in ACS applied bio materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Meng-Chen ChiangDepartment of Chemical Engineering, University of Massachusetts Amherst, Amherst, Massachusetts 01003-9303, United States.ORCID 0009-0003-3620-1533
Brandon R ClarkeDepartment of Polymer Science and Engineering, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States.ORCID 0000-0002-1423-599X
Gregory N TewDepartment of Polymer Science and Engineering, University of Massachusetts Amherst, Amherst, Massachusetts 01003, United States.ORCID 0000-0003-3277-7925
Jessica D SchiffmanDepartment of Chemical Engineering, University of Massachusetts Amherst, Amherst, Massachusetts 01003-9303, United States.ORCID 0000-0002-1265-5392

Funding

Biotechnology Training Program in Applied Life SciencesT32GM135096 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Jeanne Ann Hardy, Ashish A. Kulkarni · 2020 to 2026
$3.9M
NIGMS NIH HHS T32 GM135096
6 · The paper itself

Abstract

Mitigating the attachment of microorganisms to polymer biomaterials is critical for preventing hospital-acquired infections. Two chemical strategies to mitigate fouling include fabricating fouling-resistant surfaces, which typically present hydrophilic polymers, such as polyethylene glycol (PEG), or creating fouling-release surfaces, which are generally hydrophobic featuring polydimethylsiloxane (PDMS). Despite the demonstrated promise of employing PEG or PDMS, amphiphilic PEG/PDMS copolymer materials remain understudied. Here, for the first time, we investigated if phase-separated amphiphilic copolymers confounded microbial adhesion. We used bottlebrush amphiphilic PEG/PDMS co-networks and homopolymer networks to study bacterial adhesion across a library of gels (ϕ

Indexed as

Anti-Bacterial AgentsBiocompatible MaterialsBiofoulingHydrogelsBacterial AdhesionDimethylpolysiloxanesEscherichia coliHydrophobic and Hydrophilic InteractionsMaterials TestingParticle SizePolyethylene GlycolsStaphylococcus aureusSurface PropertiesAnti-Bacterial AgentsbaysilonBiocompatible MaterialsDimethylpolysiloxanesHydrogelsPolyethylene Glycolsamphiphilicantifoulingbottlebrushmicroorganismpolydimethylsiloxanepolyethylene glycol

Identifiers

PMID40270321
PMCPMC12091446

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.